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中华脑科疾病与康复杂志(电子版) ›› 2022, Vol. 12 ›› Issue (03) : 183 -186. doi: 10.3877/cma.j.issn.2095-123X.2022.03.012

综述

影响下丘脑激素分泌肿瘤的相关特征及研究进展
冯添顺1, 朱先理2, 王守森1,()   
  1. 1. 350025 福州,厦门大学附属东方医院(联勤保障部队第九○○医院)神经外科
    2. 310016 杭州,浙江大学邵逸夫医院神经外科
  • 收稿日期:2022-01-24 出版日期:2022-06-15
  • 通信作者: 王守森

Related characteristics and research progress of tumors affecting hypothalamic hormone secretion

Tianshun Feng1, Xianli Zhu2, Shousen Wang1,()   

  1. 1. Department of Neurosurgery, Dongfang Affiliated Hospital of Xiamen University (the 900 Hospital of Joint Logistics Team), Fuzhou 350025, China
    2. Department of Neurosurgery, Sir Run Run Hospital, Medical College, Zhejiang University, Hangzhou 310016, China
  • Received:2022-01-24 Published:2022-06-15
  • Corresponding author: Shousen Wang
引用本文:

冯添顺, 朱先理, 王守森. 影响下丘脑激素分泌肿瘤的相关特征及研究进展[J/OL]. 中华脑科疾病与康复杂志(电子版), 2022, 12(03): 183-186.

Tianshun Feng, Xianli Zhu, Shousen Wang. Related characteristics and research progress of tumors affecting hypothalamic hormone secretion[J/OL]. Chinese Journal of Brain Diseases and Rehabilitation(Electronic Edition), 2022, 12(03): 183-186.

下丘脑是人体重要的内分泌中枢,其通过分泌激素维持人体内环境稳定,并发挥神经-内分泌功能。作为内分泌系统的"启动器",下丘脑的不同功能区含有多种神经分泌细胞,负责分泌不同的激素。下丘脑及其邻近组织起源的肿瘤,包括神经节细胞瘤、神经细胞瘤、胶质瘤、错构瘤、生殖细胞瘤等,通过占位效应、异常分泌激素等方式,对下丘脑或垂体的激素分泌产生影响,从而导致多种复杂的临床症候群。本文围绕近年来影响下丘脑激素分泌的肿瘤的相关特征及研究进展综述如下。

Hypothalamus is the center of endocrine for human body, which is crucial to homeostasis and plays an irreplaceable role in regulating neuroendocrine function by secreting hypothalamic hormones. As the "initiator" of endocrine system, different functional areas of hypothalamus contain various neurosecretory cells responsible for the secretion of different hormones. Tumors of hypothalamic and adjacent tissue origin, including ganglion cell tumors, neuroblastomas, gliomas, malignant tumors and germ cell tumors, affect hormonal secretion in the hypothalamus or pituitary gland through occupying effects and abnormal secretion of hormones, resulting in a variety of complex clinical syndromes. In recent years there has been some research into tumors affecting hypothalamic hormone secretion, which is briefly reviewed here.

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