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Chinese Journal of Brain Diseases and Rehabilitation(Electronic Edition) ›› 2017, Vol. 07 ›› Issue (01): 10-12. doi: 10.3877/cma.j.issn.2095-123X.2017.01.003

Special Issue:

• Clinical Studies • Previous Articles     Next Articles

Expression and clinical significance of serum protein S100β in patients with isolated vertigo

Dan Wei1,(), Tong Li2, Yufeng Yang1, Dianyin Zhang1, Guoping Li1, Jianbo Li1, Yuqin Hou1   

  1. 1. Department of Neurology, Anyang Regional Hospital, Anyang 455000 China
    2. Department of Neurology, the First Affiliated Hospital of Xinxiang Medical University, Weihui 453100, China
  • Received:2016-07-04 Online:2017-02-01 Published:2017-02-01
  • Contact: Dan Wei
  • About author:
    Corresponding author: Wei Dan, Email:

Abstract:

Objective

To investigate the expression of serum protein S100β in patients with isolated vertigo, analyze the diagnosis effect on acute posterior circulation stroke and nonvascular vertigo, which provide the evidence for early diagnosis and treatment of isolated vertigo.

Methods

The patients with acute isolated vertigo were divided into two groups, the stroke group (50 cases) and the nonvascular vertigo group (50 cases), and the empty serum protein S100β expression levels in 24 hours was tested .

Results

The levels of serum protein S100β in the stroke group were significantly higher than the nonvascular vertigo group, with a statistical difference (t=6.456, P=0.000 ).

Conclusion

S100β could serve as a biomarker for distinguishing between acute posterior circulation stroke and nonvascular vertigo.

Key words: Isolated vertigo, Acute posterior circulation stroke, S100β

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