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Chinese Journal of Brain Diseases and Rehabilitation(Electronic Edition) ›› 2019, Vol. 09 ›› Issue (03): 154-157. doi: 10.3877/cma.j.issn.2095-123X.2019.03.007

Special Issue:

• Clinical Research • Previous Articles     Next Articles

Edaravone combined with atorvastatin calcium promote the clinical therapeutic effect of acute cerebral infarction

Mingjun Liang1, Guangrong Deng1, Xinhuan Zhen1,()   

  1. 1. Department of Emergency, Kaiping Central Hospital, Jiangmen 529300, China
  • Received:2019-05-02 Online:2019-06-15 Published:2019-06-15
  • Contact: Xinhuan Zhen
  • About author:
    Corresponding author: Zhen Xinhuan, Email:

Abstract:

Objective

To study the clinical effect of Edaravone combined with atorvastatin calcium tablets on acute cerebral infarction.

Methods

Ninety-seven patients with acute cerebral infarction admitted to Kaiping Central Hospital from January 2015 to October 2017 were selected as the study subjects. According to the difference of treatment schemes, they were divided into experimental group (using edaravone combined with atorvastatin calcium tablets) and control group (conventional treatment group). The early treatment effect, complications, and recovery ability of daily life of the two groups were compared.

Results

Compared with conventional treatment, Edaravone combined with atorvastatin significantly increased the number of basic cured cases (P<0.05), while the number of ineffective cases showed less (P<0.05), and the total effective rate was significantly higher (P<0.05). The incidence of pulmonary infection in patients was significantly lower than that in the conventional treatment group (P<0.05), while there was no significant difference in deep venous infection, bedsores, urinary tract infection and malnutrition(P>0.05), but the incidence was lower than that in the conventional treatment group. In addition, the ADL scores of patients at the 6th, 9th and 12th month of convalescence were significantly higher (P<0.05).

Conclusion

Edaravone combined with atorvastatin calcium tablets can improve the clinical effect of acute cerebral infarction.

Key words: Acute cerebral infarction, Edaravone, Atorvastatin

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