Abstract:

Cerebral proliferative angiopathy (CPA) is an extremely rare ischemic vascular malformation. Its morphology is complex and its origin is unknown. The natural evolution of CPA is different from arteriovenous malformations, and the clinical manifestations of arteriovenous malformations are different. Most patients have epilepsy, headache and progressive neurological deficits as their main symptoms. Its natural history indicates that the disease is unstable and may develop at some point in time. It is therefore important to recognize that this rare disease facilitates active surgery or other interventions to prevent permanent damage to normal brain tissue. Therefore, in order to better understand CPA, this article intends to review the progress of CPA epidemiology, pathogenesis, clinical manifestations, diagnosis and treatment.

Key words: Cerebral proliferative angiopathy, Pathogenesis, Clinical manifestations