To study the characteristics of intracranial hemangiopericytoma (HPC) and the influencing factors of recurrence.

Forty-two patients with intracranial HPC confirmed by surgery and pathology in Neurosurgery Department of Qilu Hospital of Shandong University from January 2008 to October 2018 were selected. The clinical manifestations, imaging data, surgical treatment, pathology and follow-up data of patients with intracranial HPC were summarized. Kaplan Meier univariate survival analysis and Cox multivariate analysis were used to analyze the factors influencing the recurrence of patients with HPC.

Intracranial hypertension and visual impairment were the most common symptoms. The imaging features of the tumors were homogeneous or mixed signal, some of them were cystic or solid, the boundary was unclear, and the meningeal tail sign was not obvious. The patients were followed up for 24-144 months. Univariate analysis showed that tumor location, tumor size, tumor resection degree and Ki-67 index were related factors of tumor recurrence. According to clinical experience, the invasion of venous sinus also affected the recurrence of HCP. Cox multivariate analysis showed that tumor resection degree and venous sinus invasion were independent factors of tumor recurrence.

Radical resection is the first choice for the treatment of intracranial HPC. The degree of tumor resection and the invasion of venous sinus are independent factors of tumor recurrence.