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Chinese Journal of Brain Diseases and Rehabilitation(Electronic Edition) ›› 2022, Vol. 12 ›› Issue (03): 183-186. doi: 10.3877/cma.j.issn.2095-123X.2022.03.012

• Review • Previous Articles     Next Articles

Related characteristics and research progress of tumors affecting hypothalamic hormone secretion

Tianshun Feng1, Xianli Zhu2, Shousen Wang1,()   

  1. 1. Department of Neurosurgery, Dongfang Affiliated Hospital of Xiamen University (the 900 Hospital of Joint Logistics Team), Fuzhou 350025, China
    2. Department of Neurosurgery, Sir Run Run Hospital, Medical College, Zhejiang University, Hangzhou 310016, China
  • Received:2022-01-24 Online:2022-06-15 Published:2022-08-05
  • Contact: Shousen Wang

Abstract:

Hypothalamus is the center of endocrine for human body, which is crucial to homeostasis and plays an irreplaceable role in regulating neuroendocrine function by secreting hypothalamic hormones. As the "initiator" of endocrine system, different functional areas of hypothalamus contain various neurosecretory cells responsible for the secretion of different hormones. Tumors of hypothalamic and adjacent tissue origin, including ganglion cell tumors, neuroblastomas, gliomas, malignant tumors and germ cell tumors, affect hormonal secretion in the hypothalamus or pituitary gland through occupying effects and abnormal secretion of hormones, resulting in a variety of complex clinical syndromes. In recent years there has been some research into tumors affecting hypothalamic hormone secretion, which is briefly reviewed here.

Key words: Hypothalamus, Tumors, Hormonal secretion, Treatment strategies

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