Advances in application of neuromodulation techniques in multiple system atrophy

doi:10.3877/cma.j.issn.2095-123X.2024.04.009

Abstract

Abstract:

Multiple system atrophy (MSA) is a type of atypical Parkinson's syndrome with rapid progression and poor prognosis.It brings a heavy burden to individuals, families and society.At present,symptomatic treatment is mainly adopted, but the results are not promising.In recent years, neural regulation technology has shown great potential in neurodegenerative diseases.This article mainly reviews the preliminary evidence and possibility of applying neural regulation technology to MSA treatment.

Key words: Multiple system atrophy, Atypical Parkinson's syndrome, Invasive neuromodulation, Noninvasive neuromodulation

Jing Bai, Xiaobing Li, Ya Bai, Yaqian Mu, Xin Guo, Xuedong Liu. Advances in application of neuromodulation techniques in multiple system atrophy[J]. Chinese Journal of Brain Diseases and Rehabilitation(Electronic Edition), 2024, 14(04): 239-243.

/ / Recommend

Add to citation manager EndNote|Ris|BibTeX

URL: https://zhnkjbykfzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.2095-123X.2024.04.009

https://zhnkjbykfzz.cma-cmc.com.cn/EN/Y2024/V14/I04/239

References 50

[1]	Wenning GK, Stankovic I, Vignatelli L, et al.The movement disorder society criteria for the diagnosis of multiple system atrophy[J].Mov Disord, 2022, 37(6): 1131-1148.DOI: 10.1002/mds.29005.
[2]	Foubert-Samier A, Pavy-Le Traon A, Guillet F, et al.Disease progression and prognostic factors in multiple system atrophy: a prospective cohort study[J].Neurobiol Dis, 2020, 139: 104813.DOI:10.1016/j.nbd.2020.104813.
[3]	Wenning GK, Geser F, Krismer F, et al.The natural history of multiple system atrophy: a prospective European cohort study[J].Lancet Neurol, 2013, 12(3): 264-274.DOI: 10.1016/s1474-4422(12)70327-7.
[4]	解虎涛,张建国.神经调控技术的过去、现在和未来[J].四川大学学报(医学版),2022,53(4):559-563.DOI:10.12182/20220760101.Xie HT, Zhang JG.Neuromodulation: past, present, and future[J].J Sichuan Univ (Med Sci), 2022, 53(4): 559-563.DOI: 10.12182/20220760101.
[5]	Meissner WG, Laurencin C, Tranchant C, et al.Outcome of deep brain stimulation in slowly progressive multiple system atrophy: a clinico - pathological series and review of the literature[J].Parkinsonism Relat Disord, 2016, 24: 69-75.DOI: 10.1016/j.parkreldis.2016.01.005.
[6]	Visser-Vandewalle V, Temel Y, Colle H, et al.Bilateral highfrequency stimulation of the subthalamic nucleus in patients with multiple system atrophy--parkinsonism.Report of four cases[J].J Neurosurg, 2003, 98(4): 882 - 887.DOI: 10.3171/jns.2003.98.4.0882.
[7]	Ullman M, Vedam - Mai V, Resnick AS, et al.Deep brain stimulation response in pathologically confirmed cases of multiple system atrophy[J].Parkinsonism Relat Disord,2012,18(1):86-88.DOI:10.1016/j.parkreldis.2011.09.008.
[8]	Tarsy D, Apetauerova D, Ryan P, et al.Adverse effects of subthalamic nucleus DBS in a patient with multiple system atrophy[J].Neurology, 2003, 61(2): 247-249.DOI: 10.1212/01.wnl.0000073986.74883.36.
[9]	Lopez-Cuina M, Fernagut PO, Canron MH, et al.Deep brain stimulation does not enhance neuroinflammation in multiple system atrophy[J].Neurobiol Dis, 2018, 118: 155-160.DOI: 10.1016/j.nbd.2018.07.016.
[10]	Badihian N, Jackson LM, Klassen BT, et al.The effects of deep brain stimulation in patients with multiple system atrophy[J].J Parkinsons Dis, 2022, 12(8): 2595 - 2600.DOI: 10.3233/jpd -223504.
[11]	Di Luca DG, Ramirez-Gomez C, Germann J, et al.Deep brain stimulation of the globus pallidus internus and externus in multiple system atrophy[J].Mov Disord,2023,38(11):2121-2125.DOI:10.1002/mds.29573.
[12]	Zhu XY, Pan TH, Ondo WG, et al.Effects of deep brain stimulation in relatively young - onset multiple system atrophy parkinsonism[J].J Neurol Sci, 2014, 342(1 -2): 42 -44.DOI:10.1016/j.jns.2014.04.022.
[13]	Artusi CA, Rinaldi D, Balestrino R, et al.Deep brain stimulation for atypical parkinsonism: a systematic review on efficacy and safety[J].Parkinsonism Relat Disord, 2022, 96: 109-118.DOI:10.1016/j.parkreldis.2022.03.002.
[14]	脊髓电刺激治疗慢性疼痛专家共识编写组.脊髓电刺激治疗慢性疼痛专家共识[J].中国疼痛医学杂志, 2021, 27(6): 406-409.DOI:10.3969/j.issn.1006-9852.2021.06.002.Expert consensus writing group on spinal cord electrical stimulation for chronic pain treatment.Expert consensus on spinal cord stimulation for chronic pain[J].Chin J Pain Med,27(6):406-409.DOI:10.3969/j.issn.1006-9852.2021.06.002.
[15]	孙荣辉,宋健,管江衡,等.脊髓电刺激术治疗遗传性脊髓小脑性共济失调1例报道并文献复习[J].中国临床神经外科杂志,2022,27(7):537-540.DOI:10.13798/j.issn.1009-153X.2022.07.003.Sun RH, Song J, Guan JH, et al.Clinical efficacy of spinal cord stimulation for gait dysfunction in patients with hereditary spinocerebellar ataxia type 6: report of one case and literature review[J].Chin J Clin Neurosurg, 2022, 27(7): 537-540.DOI: 10.13798/j.issn.1009-153X.2022.07.003.
[16]	黄佳彬,李迪森,罗裕辉,等.脊髓电刺激治疗不宁腿综合征3例及文献复习[J].中国疼痛医学杂志,2023,29(1):74-78.DOI:10.3969/j.issn.1006-9852.2023.01.014.Huang JB, Li DS, Luo YH, et al.Three cases of restless legs syndrome treated by spinal cord stimulation and literature review[J].Chin J Pain Med, 2023, 29(1): 74-78.DOI: 10.3969/j.issn.1006-9852.2023.01.014.
[17]	袁邦清,陈邱明,杨光,等.脊髓电刺激治疗严重意识障碍的临床疗效分析[J].中华神经外科疾病研究杂志,2018,17(4):369-370.Yuan BQ,Chen QM,Yang G,et al.Clinical efficacy of spinal cord electrical stimulation in the treatment of severe disturbance of consciousness[J].Chin J Neurosurg Dis Res, 2018, 17(4): 369-370.
[18]	Agari T, Date I.Spinal cord stimulation for the treatment of abnormal posture and gait disorder in patients with Parkinson's disease[J].Neurol Med Chir (Tokyo), 2012, 52(7): 470-474.DOI:10.2176/nmc.52.470.
[19]	Samotus O, Parrent A, Jog M.Spinal cord stimulation therapy for gait dysfunction in advanced Parkinson's disease patients[J].Mov Disord,2018,33(5):783-792.DOI:10.1002/mds.27299.
[20]	Zhang Y, Song T, Zhuang P, et al.Spinal cord stimulation improves freezing of gait in a patient with multiple system atrophy with predominant parkinsonism[J].Brain Stimul,2020,13(3):653-654.DOI:10.1016/j.brs.2020.02.006.
[21]	Wang L, Zhu R, Pan Y, et al.Effects of high cervical spinal cord stimulation on gait disturbance and dysarthropneumophonia in Parkinson's disease and Parkinson variant of multiple system atrophy: a case series[J].Brain Sci, 2022, 12(9): 1222.DOI:10.3390/brainsci12091222.
[22]	Gong H, Liu Y, Zhu X, et al.Spinal cord stimulation improved freezing of gait and hypokinetic dysarthria of a patient with dopamine-resistant multiple system atrophy-parkinsonian type[J].Neurol India, 2022, 70(2): 757-759.DOI: 10.4103/0028-3886.344653.
[23]	Ciocca M,Seemungal BM,Tai YF.Spinal cord stimulation for gait disorders in Parkinson's disease and atypical parkinsonism: a systematic review of preclinical and clinical data[J].Neuromodulation,2023,26(7):1339-1361.DOI:10.1016/j.neurom.2023.06.003.
[24]	Li J, Mei S, Zhang X, et al.Case report: combined therapy of bilateral subthalamic nucleus deep brain stimulation and spinal cord stimulation significantly improves motor function in a patient with multiple system atrophy with predominant parkinsonism[J].Front Neurosci,2022,16:929273.DOI:10.3389/fnins.2022.929273.
[25]	Millar Vernetti P.Epidural spinal cord stimulation to treat neurogenic orthostatic hypotension in multiple system atrophy: a new hope?[J].Mov Disord Clin Pract, 2022, 9(8): 1025-1026.DOI:10.1002/mdc3.13583.
[26]	Squair JW, Berney M, Castro Jimenez M, et al.Implanted system for orthostatic hypotension in multiple-system atrophy[J].N Engl J Med,2022,386(14):1339-1344.DOI:10.1056/NEJMoa2112809.
[27]	Zhu X, Huang S, Li N, et al.Cervical spinal cord stimulation for sleep-disordered breathing in multiple system atrophy[J].Brain Stimul,2023,16(3):854-856.DOI:10.1016/j.brs.2023.05.001.
[28]	Greenberg DR, Sohlberg EM, Zhang CA, et al.Sacral nerve stimulation in Parkinson's disease patients with overactive bladder symptoms[J].Urology,2020,144:99-105.DOI:10.1016/j.urology.2020.06.063.
[29]	Martin S, Zillioux J, Goldman HB.Is sacral neuromodulation effective in patients with Parkinson's disease?A retrospective review[J].Neurourol Urodyn, 2022, 41(4): 955 - 961.DOI: 10.1002/nau.24900.
[30]	Zhang C, Wang L, Pan Y, et al.Sacral nerve stimulation improves gait in Parkinson's disease[J].Brain Stimul, 2019, 12(4): 1075-1076.DOI:10.1016/j.brs.2019.03.074.
[31]	Kobayashi M, Pascual-Leone A.Transcranial magnetic stimulation in neurology[J].Lancet Neurol,2003,2(3):145-156.DOI:10.1016/s1474-4422(03)00321-1.
[32]	Petsani C,Aloizou AM,Siokas V,et al.Therapeutic application of rtms in atypical parkinsonian disorders[J].Behav Neurol, 2021,2021:3419907.DOI:10.1155/2021/3419907.
[33]	Liu Z, Ma H, Poole V, et al.Effects of multi-session repetitive transcranial magnetic stimulation on motor control and spontaneous brain activity in multiple system atrophy: a pilot study[J].Front Behav Neurosci, 2018, 12: 90.DOI: 10.3389/fnbeh.2018.00090.
[34]	França C, de Andrade DC, Silva V, et al.Effects of cerebellar transcranial magnetic stimulation on ataxias: a randomized trial[J].Parkinsonism Relat Disord, 2020, 80: 1-6.DOI: 10.1016/j.parkreldis.2020.09.001.
[35]	Chen XY, Lian YH, Liu XH, et al.Effects of repetitive transcranial magnetic stimulation on cerebellar metabolism in patients with spinocerebellar ataxia type 3[J].Front Aging Neurosci,2022,14:827993.DOI:10.3389/fnagi.2022.827993.
[36]	Marsden J, Harris C.Cerebellar ataxia: pathophysiology and rehabilitation[J].Clin Rehabil, 2011, 25(3): 195-216.DOI: 10.1177/0269215510382495.
[37]	Song P, Li S, Wang S, et al.Repetitive transcranial magnetic stimulation of the cerebellum improves ataxia and cerebello-fronto plasticity in multiple system atrophy: a randomized, double-blind,sham-controlled and TMS-EEG study[J].Aging (Albany NY),2020,12(20):20611-20622.DOI:10.18632/aging.103946.
[38]	Grimaldi G, Argyropoulos GP, Boehringer A, et al.Non-invasive cerebellar stimulation--a consensus paper[J].Cerebellum, 2014,13(1):121-138.DOI:10.1007/s12311-013-0514-7.
[39]	Chou YH, You H, Wang H, et al.Effect of repetitive transcranial magnetic stimulation on fMRI resting - state connectivity in multiple system atrophy[J].Brain Connect, 2015, 5(7): 451-459.DOI:10.1089/brain.2014.0325.
[40]	Yildiz FG, Saka E, Elibol B, et al.Modulation of cerebellarcortical connections in multiple system atrophy type C by cerebellar repetitive transcranial magnetic stimulation[J].Neuromodulation,2018,21(4):402-408.DOI:10.1111/ner.12589.
[41]	Pan J,Mi TM,Ma JH,et al.High-frequency repetitive transcranial magnetic stimulation over the left dorsolateral prefrontal cortex shortly alleviates fatigue in patients with multiple system atrophy:a randomized controlled trial[J].Front Neurol, 2021, 12: 755352.DOI:10.3389/fneur.2021.755352.
[42]	Benussi A,Koch G,Cotelli M,et al.Cerebellar transcranial direct current stimulation in patients with ataxia: a double - blind,randomized, sham-controlled study[J].Mov Disord, 2015, 30(12):1701-1705.DOI:10.1002/mds.26356.
[43]	Alexoudi A, Patrikelis P, Fasilis T, et al.Effects of anodal tDCS on motor and cognitive function in a patient with multiple system atrophy[J].Disabil Rehabil, 2020, 42(6): 887-891.DOI: 10.1080/09638288.2018.1510043.
[44]	Ahn JH,Lee D,Kim M,et al.M1 and cerebellar tDCS for MSA-C:a double-blind, randomized, sham-controlled, crossover study[J].Cerebellum, 2023, 22(3): 386-393.DOI: 10.1007/s12311-022-01416-1.
[45]	吴绍伟.迷走神经电刺激术治疗神经系统疾病的应用进展[J].中华脑科疾病与康复杂志(电子版),2023,13(3):180-184.DOI:10.3877/cma.j.issn.2095-123X.2023.03.009.Wu SW.Recent advance in clinical application of vagus nerve stimulation in improving neurological disorders[J].Chin J Brain Dis Rehabil (Electronic Edition), 2023, 13(3): 180-184.DOI:10.3877/cma.j.issn.2095-123X.2023.03.009.
[46]	Zhang H, Cao XY, Wang LN, et al.Transcutaneous auricular vagus nerve stimulation improves gait and cortical activity in Parkinson's disease: a pilot randomized study[J].CNS Neurosci Ther,2023,29(12):3889-3900.DOI:10.1111/cns.14309.
[47]	Marano M,Anzini G,Musumeci G,et al.Transcutaneous auricular vagus stimulation improves gait and reaction time in Parkinson's disease[J].Mov Disord, 2022, 37(10): 2163-2164.DOI: 10.1002/mds.29166.
[48]	Mondal B, Choudhury S, Simon B, et al.Noninvasive vagus nerve stimulation improves gait and reduces freezing of gait in Parkinson's disease[J].Mov Disord, 2019, 34(6): 917-918.DOI:10.1002/mds.27662.
[49]	Ko DWK.Transcutaneous vagus nerve stimulation (tVNS) as a potential therapeutic application for neurodegenerative disordersa focus on dysautonomia in Parkinson's disease[J].Auton Neurosci,2021,235:102858.DOI:10.1016/j.autneu.2021.102858.
[50]	Sigurdsson HP, Hunter H, Alcock L, et al.Safety and tolerability of adjunct non-invasive vagus nerve stimulation in people with Parkinson's: a study protocol[J].BMC Neurol, 2023, 23(1): 58.DOI:10.1186/s12883-023-03081-1.

Please choose a citation manager

Content to export