Clinical study on the serverity evaluation after subarachnoid hemorrhage by disturbance coefficient of non-invasive brain edema monitor

doi:10.3877/cma.j.issn.2095-123X.2024.06.004

Abstract

Abstract:

Objective

To evaluate the correlation between the disturbance coefficient （DC） of a non-invasive brain edema monitor and the severity of patients with aneurysmal subarachnoid hemorrhage（SAH）.

Methods

The clinical data of 121 patients with aneurysmal SAH and 60 patients with unruptured aneurysm in the Neurosurgery Department of General Hospital Northern Theater Command from September 2020 to June 2021 were analyzed. The severity of the patient's condition was evaluated using modified Fisher （mFisher） score，GCS score，and Hent-Hess （H-H） grading. The DC value was measured using a non-invasive brain edema dynamic detector，and the relationship between DC value and mFisher score，GCS score，and H-H grading was analyzed using the Spearman method.

Results

The DC value of patients with aneurysmal SAH （169.38±2.24） was higher than that of patients without ruptured aneurysm（127.84±1.95），and the difference was statistically significant （P＜0.01）.The DC values of aneurysmal SAH patients with mild，moderate，and severe consciousness disorders were compared pairwise，and the differences were statistically significant （P＜0.01）； The DC value of patients with mild aneurysmal SAH is higher than that of patients with unruptured aneurysm，and the difference was statistically significant （P＜0.01）. The DC values of H-H Ⅱ，Ⅲ，and Ⅳpatients were compared pairwise，and the differences were statistically significant （P＜0.01）； The average DC value of patients with H-H grade Ⅰ-Ⅱaneurysmal SAH is higher than that of patients with unruptured aneurysm，and the difference was statistically significant （P＜0.01）. The DC values of mFisher Ⅱ，Ⅲ，and Ⅳpatients were compared pairwise，and the differences were statistically significant （P＜0.01）； The average DC value of mFisher grade Ⅰ-Ⅱaneurysmal SAH patients was higher than that of patients with unruptured aneurysm，and the difference was statistically significant （P＜0.01）. The DC value was correlated with GCS score and H-H grading （r=-0.743，-0.713，P＜0.001），and has a weak correlation with mFisher grading （r=-0.512，P＜0.001）.

Conclusion

The DCs among H-H Ⅱ，Ⅲ，Ⅳwere different，indicated DC value of the third generation of non-invasive brain edema monitor can sensitively reflact the condition of SAH patients，which provide benefit for patient.

Key words: Non-invasive brain edema monitor, Disturbance coefficient, Subarachnoid hemorrhage, Early brain injury, Illness condition evaluation

Pengyu Pan, Gen Li, Dongdong Liu, Rui Kong, Youcheng Li, Jiashuo Li, Xinyu Yang, Wenxu Zhang, Zechao Zhu, Xueshi Tian, Liang Wen, Wei Jiang, Tingzhun Zhu, Hua Feng, Guobiao Liang. Clinical study on the serverity evaluation after subarachnoid hemorrhage by disturbance coefficient of non-invasive brain edema monitor[J]. Chinese Journal of Brain Diseases and Rehabilitation(Electronic Edition), 2024, 14(06): 341-345.

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Figures/Tables 4

Fig.1 Comparison of DC values between aneurysmal SAH patients and unruptured aneurysms patients

Fig.2 Comparison of DC values of patients with different Hent-Hess of aneurysmal SAH

Fig.3 Comparison of DC values of patients with aneurysmal SAH with different degrees of consciousness disorders

Fig.4 Comparison of DC values of aneurysmal SAH patients with different mFisher scores

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