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中华脑科疾病与康复杂志(电子版) ›› 2023, Vol. 13 ›› Issue (05) : 299 -303. doi: 10.3877/cma.j.issn.2095-123X.2023.05.007

临床研究

锥颅血肿外引流与神经内镜手术治疗老年基底节区高血压性脑出血的疗效分析
刘政委(), 仪立志, 尹夕龙, 孔文龙, 纠智松, 张文源   
  1. 518116 深圳市龙岗中心医院(广州中医药大学深圳临床医学院)神经外科
  • 收稿日期:2022-10-10 出版日期:2023-10-15
  • 通信作者: 刘政委

Efficacy analysis of external drainage of conocephalic hematoma and neuroendoscopic surgery for senile hypertensive intracerebral hemorrhage in basal ganglia

Zhengwei Liu(), Lizhi Yi, Xilong Yin, Wenlong Kong, Zhisong Jiu, Wenyuan Zhang   

  1. Department of Neurosurgery, Longgang Central Hospital (Shenzhen College of Clinical Medicine, Guangzhou University of Traditional Chinese Medicine), Shenzhen 518116, China
  • Received:2022-10-10 Published:2023-10-15
  • Corresponding author: Zhengwei Liu
  • Supported by:
    Special Fund for Science and Technology Development of Longgang District, Shenzhen City, Guangdong Province(LGkcylws2020013)
引用本文:

刘政委, 仪立志, 尹夕龙, 孔文龙, 纠智松, 张文源. 锥颅血肿外引流与神经内镜手术治疗老年基底节区高血压性脑出血的疗效分析[J/OL]. 中华脑科疾病与康复杂志(电子版), 2023, 13(05): 299-303.

Zhengwei Liu, Lizhi Yi, Xilong Yin, Wenlong Kong, Zhisong Jiu, Wenyuan Zhang. Efficacy analysis of external drainage of conocephalic hematoma and neuroendoscopic surgery for senile hypertensive intracerebral hemorrhage in basal ganglia[J/OL]. Chinese Journal of Brain Diseases and Rehabilitation(Electronic Edition), 2023, 13(05): 299-303.

目的

探讨颅内压监护下血肿穿刺外引流术和神经内镜结合球囊通道辅助下血肿清除术治疗老年基底节区高血压性脑出血(HICH)患者的临床疗效。

方法

选取深圳市龙岗中心医院神经外科自2017年8月至2021年2月收治的68例老年基底节区HICH患者,按照随机数字表法分为锥颅组和内镜组,每组34例。锥颅组采用颅内压监护下血肿穿刺外引流术,内镜组采用神经内镜结合球囊通道辅助下血肿清除手术。比较2组患者的手术时间、术后第2天的血肿清除率、甘露醇使用时间、住院时间、住院费用、手术并发症(肺部感染、深静脉血栓)发生率和术后6个月的GOSE评分,分析其临床疗效。

结果

锥颅组的手术时间[19.5(15.23,22.47)min]、住院时间[(14.53±3.05)d]明显短于内镜组[84.23(75.25,91.80)min、(30.89±9.53)d],术后第2天的血肿清除率(53.67%±13.10%)低于内镜组(87.80%±6.10%),甘露醇使用时间[2.00(0.00,3.75)d]长于内镜组[0.00(0.00,1.00)d],住院费用[(2.39±0.45)万元]少于内镜组[(5.21±1.30)万元],差异均具有统计学意义(P<0.05)。2组患者肺部感染率、深静脉血栓发生率和术后6个月GOSE评分比较,差异均无统计学意义(P>0.05)。2组均无患者死亡。

结论

对于老年基底节区HICH患者,颅内压监护下血肿穿刺外引流术较神经内镜结合球囊通道辅助下血肿清除手术效率高、住院时间短、预后更优,而且可以减轻患者及其家庭的经济压力。

Objective

To explore the clinical efficacy of hematoma puncture and external drainage under intracranial pressure monitoring and neuroendoscopy combined with balloon channel assisted hematoma evacuation in the treatment of elderly patients with hypertensive intracerebral hemorrhage (HICH) in the basal ganglia region.

Methods

From August 2017 to February 2021, 68 elderly patients with basal ganglia HICH admitted to the Neurosurgery Department of Longgang Central Hospital in Shenzhen were randomly divided into a cone group and an endoscopic group, with 34 cases in each group. The cone group underwent hematoma puncture and external drainage under intracranial pressure monitoring, while the endoscopic group underwent hematoma evacuaton with the assistance of neuroendoscopy combined with balloon channel. The surgical time, hematoma clearance rate on the second day after surgery, mannitol use time, length of hospitlization, hospitalization costs, incidence of surgical complications (pulmonary infection, deep vein thrombosis), and GOSE score at 6 months after surgery were compared between two groups of patients, and their clinical efficacy were analyzed.

Results

The surgical time [19.5 (15.23, 22.47) min] and the hospitalization time was [(14.53±3.05) d] in the cone group were significantly shorter than those in the endoscopic group [84.23 (75.25, 91.80) min, (30.89±9.53) d]. The hematoma clearance rate on the second day after surgery (53.67%±13.10%) was lower than that in the endoscopic group (87.80%±6.10%), and the use time of mannitol [2.00 (0.00, 3.75) d] was longer than that in the endoscopic group [0.00 (0.00, 1.00) d]. The hospitalization cost (23 900±4 500) yuan was less than that in the endoscopic group (52 100±13 000) yuan, the differences were statistically significant (P<0.05). There was no statistically significant difference in the incidence of surgical complications such as pulmonary infection, deep vein thrombosis, and GOSE scores at 6 months after surgery between the two groups of patients (P>0.05). Both groups had no patient deaths.

Conclusion

For elderly patients with HICH in the basal ganglia, hematoma puncture and external drainage under intracranial pressure monitoring is more efficient than neuroendoscopy combined with balloon channel assisted hematoma evacuation, with shorter hospital stay, and better prognosis, and it can also reduce the economic pressure on patients and their families.

表1 2组患者术前临床资料比较
Tab.1 General preoperative information of the endoscopic surgery group and conical surgery group
图1 颅内压监护下血肿穿刺外引流术影像资料A:颅内血肿定位;B:穿刺;C:引流;D:拔管
Fig.1 Imaging data of neuroendoscopy combined with balloon assisted hematoma removal
表2 2组患者治疗指标的比较
Tab.2 Comparison of operation and treatment related indexes between two groups
表3 2组患者术后并发症发生情况和预后比较
Tab.3 Comparison of postoperative complications and prognosis between two groups
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