To study the application value of various parameters in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in evaluating the blood supply of acoustic schwannoma, and to provide objective analysis basis for clinical treatment of acoustic schwannoma.

Sixteen patients with acoustic schwannoma admitted to neurosurgery department of the Affiliated Brain Hospital of Nanjing Medical University from September 2019 to January 2021 were selected as the research objects, and 8 patients without acoustic schwannoma history were selected as the control group. Sixteen cases of acoustic neurilemmoma were performed conventional MRI scan and contrast enhancement before operation, and then underwent DCE-MRI scan. After injection of contrast agent, they were divided into internal auditory canal group (6 cases) and intracranial group (10 cases) according to the enhancement site of DCE-MRI image; the control group underwent DCE-MRI scan. All DCE-MRI images were post processed by Philips image processing workstation to obtain tic curve and semi quantitative parameters, including maximum signal intensity (SImax), time to peak (TTP), maximum slope of increase (MSI), wash in rate (WIR). The time signal intensity curve (TIC) types and semi-quantitative parameter values of the control group, internal auditory canal group and intracranial group were statistically analyzed, and the χ² test and Kruskal-Wallis test were used for comparison between groups.

In the control group, TICs of type Ⅰ, Ⅱ and Ⅲ were 8, 0, and 0 cases, respectively. In the internal auditory canal group, TICs of type Ⅰ, Ⅱ and Ⅲ were 0, 1, and 5 cases, respectively. In the intracranial group, TICs were Ⅰ, Ⅱ and Ⅲ were 4, 6, and 0 cases, respectively. The difference between the control group and the internal auditory canal group, intracranial group was statistically significant (P<0.05); Comparing the internal auditory canal group with the intracranial group, the difference was statistically significant (P<0.05). SImax, TTP, MSI, WIR of control group are all lower than those of the internal auditory canal group and the intracranial group, the differences were statistically significant (P<0.05). There were no significant differences in SImax, TTP, WIR between the internal auditory canal group and the intracranial group (P>0.05); MSI in the internal auditory canal group was higher than that in the intracranial group (P<0.05).

The TIC of DCE-MRI and the MSI in the semi quantitative parameters have certain significance for identifying whether the blood supply of acoustic schwannomas is transcranial (vertebral-basal artery system) or internal auditory canal (external carotid artery branch).