Comparison of clinical application of polyetheretherketone and titanium mesh in cranioplasty

doi:10.3877/cma.j.issn.2095-123X.2021.06.009

Abstract

Abstract:

Objective

To compare clinical application effects of polyetheretherketone (PEEK) and titanium mesh in cranioplasty.

Methods

The clinical data of 138 patients with cranioplasty treated in the Department of Neurosurgery of the Fifth Affiliated Hospital of Zhengzhou University from January 2018 to June 2021 were retrospectively analyzed. The patients were divided into PEEK group(n=36) and titanium mesh group (n=102) according to materials used in cranioplasty. The postoperative complications and plastic satisfaction were compared between two groups.

Results

There were no significant differences in epidural hematoma, infection, epilepsy, repair material exposure or deformation, and incidence of secondary operations between two groups (P>0.05). The incidence of subcutaneous fluid in PEEK group was significantly higher than that in titanium mesh group (P<0.05). The plastic satisfaction in PEEK group was significantly superior to that of titanium mesh group (P<0.05).

Conclusion

PEEK, a neotype skull repair material, is safe and effective in cranioplasty, and plastic satisfaction is better, but the cost is higher. Therefore, PEEK can be regarded as an ideal skull repair material for patients with economic basis and higher requirements in external appearance and subjective comfort following cranioplasty.

Key words: Cranial defect, Cranioplasty, Polyetheretherketone, Titanium mesh

Dexiao Zhao, Yongkun Guo, Xinjun Wang, Wanqing Liu, Guanqi Chen, Jianchao Mao, Qiao Shan. Comparison of clinical application of polyetheretherketone and titanium mesh in cranioplasty[J]. Chinese Journal of Brain Diseases and Rehabilitation(Electronic Edition), 2021, 11(06): 362-365.

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References 24

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项目		PEEK组（n=36）	钛网组（n=102）	χ²/t值	P值
性别[例（%）]				0.523	0.470
	男	28（77.8）	73（74.7）
	女	8（22.2）	29（27.3）
年龄（岁，Mean±SD）		45.1±12.7	47.1±13.1	-0.792	0.430
颅骨缺损部位[例（%）]				0.467	0.792
	左侧	13（36.1）	31（30.4）
	右侧	21（58.3）	66（64.7）
	双侧	2（5.6）	5（4.9）
颅骨缺损病因[例（%）]				0.548	0.760
	脑外伤	20（55.6）	56（54.9）
	自发性脑出血	15（41.7）	40（39.2）
	脑梗死	1（2.8）	6（5.9）
颅骨缺损面积（cm²，Mean±SD）		105.9±38.7	105.1±36.8	0.109	0.913
颅骨缺损时间（月，Mean±SD）		4.6±2.9	5.1±2.9	-1.006	0.316

项目		PEEK组（n=36）	钛网组（n=102）	χ²/t值	P值
性别[例（%）]				0.523	0.470
	男	28（77.8）	73（74.7）
	女	8（22.2）	29（27.3）
年龄（岁，Mean±SD）		45.1±12.7	47.1±13.1	-0.792	0.430
颅骨缺损部位[例（%）]				0.467	0.792
	左侧	13（36.1）	31（30.4）
	右侧	21（58.3）	66（64.7）
	双侧	2（5.6）	5（4.9）
颅骨缺损病因[例（%）]				0.548	0.760
	脑外伤	20（55.6）	56（54.9）
	自发性脑出血	15（41.7）	40（39.2）
	脑梗死	1（2.8）	6（5.9）
颅骨缺损面积（cm²，Mean±SD）		105.9±38.7	105.1±36.8	0.109	0.913
颅骨缺损时间（月，Mean±SD）		4.6±2.9	5.1±2.9	-1.006	0.316

组别	例数	硬膜外血肿	感染	癫痫	皮下积液	修补材料外露	修补材料变形	二次手术
PEEK组	36	0（0）	2（5.6）	2（5.6）	7（19.4）	0（0）	0（0）	1（2.8）
钛网组	102	3（2.9）	4（3.9）	8（7.8）	6（5.9）	4（3.9）	3（2.9）	8（7.8）
χ²值				0.007	4.256			0.443
P值		0.567	0.651	0.935	0.039	0.573	0.567	0.506

组别	例数	硬膜外血肿	感染	癫痫	皮下积液	修补材料外露	修补材料变形	二次手术
PEEK组	36	0（0）	2（5.6）	2（5.6）	7（19.4）	0（0）	0（0）	1（2.8）
钛网组	102	3（2.9）	4（3.9）	8（7.8）	6（5.9）	4（3.9）	3（2.9）	8（7.8）
χ²值				0.007	4.256			0.443
P值		0.567	0.651	0.935	0.039	0.573	0.567	0.506

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