Current progress in surgical targets of deep brain stimulation for obsessive-compulsive disorder

doi:10.3877/cma.j.issn.2095-123X.2022.01.008

Abstract

Abstract:

About 40%-60% obsessive-compulsive disorder patients respond poorly to multimodal comprehensive treatment including drugs, psychotherapy and other treatment methods, and further progress to refractory obsessive-compulsive disorder. Deep brain stimulation (DBS) can regulate the abnormal cortico-striato-thalamocortical circuit to reduce the symptoms of obsessive-compulsive disorder. This article summarizes the progress of different DBS surgical strategies for obsessive-compulsive disorder, and systematically reviewed the neuroimaging studies on the effects of DBS on the brain network of obsessive-compulsive disorder patients.

Key words: Obsessive-compulsive disorder, Deep brain stimulation, Neuroimaging, Brain network, Neural circuit

Weibin He, Chenhui Li, Gaohua Wang, Wei Yi. Current progress in surgical targets of deep brain stimulation for obsessive-compulsive disorder[J]. Chinese Journal of Brain Diseases and Rehabilitation(Electronic Edition), 2022, 12(01): 49-53.

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