切换至 "中华医学电子期刊资源库"

中华脑科疾病与康复杂志(电子版) ›› 2021, Vol. 11 ›› Issue (05) : 282 -284. doi: 10.3877/cma.j.issn.2095-123X.2021.05.006

脑科疾病与康复

头颅CTA检查在微血管减压术前安全性评估中的临床意义
种玉龙1, 徐武1, 王晶1, 姜成荣1, 梁维邦1,()   
  1. 1. 210008 南京,南京大学医学院附属鼓楼医院神经外科
  • 收稿日期:2021-09-20 出版日期:2021-10-15
  • 通信作者: 梁维邦

Clinical significance of cranial CTA in safety assessment before microvascular decompression

Yulong Chong1, Wu Xu1, Jing Wang1, Chengrong Jiang1, Weibang Liang1,()   

  1. 1. Department of Neurosurgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, China
  • Received:2021-09-20 Published:2021-10-15
  • Corresponding author: Weibang Liang
引用本文:

种玉龙, 徐武, 王晶, 姜成荣, 梁维邦. 头颅CTA检查在微血管减压术前安全性评估中的临床意义[J]. 中华脑科疾病与康复杂志(电子版), 2021, 11(05): 282-284.

Yulong Chong, Wu Xu, Jing Wang, Chengrong Jiang, Weibang Liang. Clinical significance of cranial CTA in safety assessment before microvascular decompression[J]. Chinese Journal of Brain Diseases and Rehabilitation(Electronic Edition), 2021, 11(05): 282-284.

目的

探讨头颅CT血管造影(CTA)检查在微血管减压术(MVD)前安全性评价中的指导意义。

方法

回顾性分析南京鼓楼医院神经外科自2018年1月至2019年6月收治的明确诊断为原发性面肌痉挛及三叉神经痛患者的临床资料。所有患者术前均采用头颅CTA检查,以高龄(≥60岁)或合并基础疾病(如高血压、高血脂、糖尿病)患者为A组,余患者为B组,分析2组术前颅内动脉瘤检出率。按照治疗方式将A组分为2个亚组,其中检出颅内动脉瘤接受血管内治疗后再行MVD的患者为观察组,余首次行MVD的患者为对照组,观察2组患者的疗效及并发症发生情况。

结果

A组患者347例,其中动脉瘤23例,检出率6.63%;B组患者191例,其中动脉瘤3例,检出率1.57%,A组动脉瘤的检出率明显高于B组,差异具有统计学意义(P<0.05)。观察组术后治愈率和好转率分别为89.47%、10.53%,对照组治愈率和好转率分别为93.43%、5.11%,疗效相近,差异无统计学意义(P>0.05)。观察组与对照组术后并发症发生率分别为10.53%、9.48%,差异无统计学意义(P>0.05)。

结论

MVD术前头颅CTA检查能够有效地发现潜在血管隐患,尤其对高龄或合并基础疾病的患者,排除手术禁忌,指导手术治疗,对MVD手术安全性评价具有重要指导意义,且动脉瘤患者血管病变治疗干预后再行MVD手术的疗效及安全性仍是可靠的。

Objective

To explore the guiding significance of cranial CT angiography (CTA) in preoperative safety assessment of microvascular decompression (MVD) patients.

Methods

The clinical data of patients with primary hemifacial spasm and trigeminal neuralgia treated in the Neurosurgery Department of Nanjing Drum Tower Hospital from January 2018 to June 2019 were analyzed retrospectively. All patients were examined by head CTA before operation. Patients aged over 60 years old or with underlying diseases (such as hypertension, hyperlipidemia, diabetes) were A group. The remaining patients were B group. The detection rate of intracranial aneurysms in group A and B was analyzed. Group A was divided into two subgroups according to the treatment method. The patients with intracranial aneurysms who underwent MVD after intravascular treatment were the observation group, and the other patients who underwent MVD for the first time were the control group. The curative effects and complications of the two groups were observed.

Results

In group A, there were 347 cases, of which 23 cases (6.63%) were found aneurysms. In group B, aneurysms were detected in 3 (1.57%) of 191 cases, and the detection rate of aneurysms in group A was significantly higher than that in group B (P<0.05). The postoperative cure rate and recovery rate of the observation group were 89.47% and 10.53%, respectively. The cure rate and recovery rate of the control group were 93.43% and 5.11%. The total incidence of postoperative complications in the observation group and the control group was 10.53% and 9.48%, without significant difference (P>0.05).

Conclusion

Cranial CTA examination before MVD can effectively detect potential vascular hazards in MVD patients. Especially for elderly patients or patients with underlying diseases, exclusion of surgical contraindications and guidance for surgical treatment are of great guiding significance for the safety evaluation of MVD surgery. Moreover, the efficacy and safety of MVD surgery after intervention for vascular lesions of aneurysms are still reliable.

表1 2组患者的颅内动脉瘤阳性率比较[例(%)]
表2 观察组与对照组MVD手术疗效及并发症比较[例(%)]
[1]
Lv MY, Deng SL, Long XF, et al. Long-term outcome of microvascular decompression for hemifacial spasm[J]. Br J Neurosurg, 2017, 31(3): 322-326.
[2]
Xia L, Zhong J, Zhu J, et al. Effectiveness and safety of microvascular decompression surgery for treatment of trigeminal neuralgia: a systematic review[J]. J Craniofac Surg, 2014, 25(4): 1413-1417.
[3]
Lee MH, Jee TK, Lee JA, et al. Postoperative complications of microvascular decompression for hemifacial spasm: lessons from experience of 2040 cases[J]. Neurosurg Rev, 2016, 39(1): 151-158; discussion 158.
[4]
Mori K, Wada K, Otani N, et al. Validation of effectiveness of keyhole clipping in nonfrail elderly patients with unruptured intracranial aneurysms[J]. J Neurosurg, 2017, 127(6): 1307-1314.
[5]
Wilkinson HA. Hypertension, age, and location predict rupture of small intracranial aneurysms[J]. Neurosurgery, 2007, 61(6): E1340.
[6]
Wu X, Matouk CC, Mangla R, et al. Cost-effectiveness of computed tomography angiography in management of tiny unruptured intracranial aneurysms in the United States[J]. Stroke, 2019, 50(9): 2396-2403.
[7]
Karp BI, Alter K. Botulinum toxin treatment of blepharospasm, orofacial/oromandibular dystonia, and hemifacial spasm[J]. Semin Neurol, 2016, 36(1): 84-91.
[8]
De Toledo IP, Conti Réus J, Fernandes M, et al. Prevalence of trigeminal neuralgia: a systematic review[J]. J Am Dent Assoc, 2016, 147(7): 570-576.e2.
[9]
Ajiboye N, Chalouhi N, Starke RM, et al. Unruptured cerebral aneurysms: evaluation and management[J]. ScientificWorldJournal, 2015, 2015: 954954.
[10]
Andrade L, Hoskoppal A, Hunt Martin M, et al. Intracranial aneurysm and coarctation of the aorta: prevalence in the current era[J]. Cardiol Young, 2021, 31(2): 229-232.
[11]
Kleinloog R, de Mul N, Verweij BH, et al. Risk factors for intracranial aneurysm rupture: a systematic review[J]. Neurosurgery, 2018, 82(4): 431-440.
[12]
Frank H, Heusser K, Geiger H, et al. Temporary reduction of blood pressure and sympathetic nerve activity in hypertensive patients after microvascular decompression[J]. Stroke, 2009, 40(1): 47-51.
[13]
Sasaki S, Tanda S, Hatta T, et al. Neurovascular decompression of the rostral ventrolateral medulla decreases blood pressure and sympathetic nerve activity in patients with refractory hypertension[J]. J Clin Hypertens (Greenwich), 2011, 13(11): 818-820.
[14]
Pyysalo L, Luostarinen T, Keski-Nisula L, et al. Long-term excess mortality of patients with treated and untreated unruptured intracranial aneurysms[J]. J Neurol Neurosurg Psychiatry, 2013, 84(8): 888-892.
[15]
Harroud A, Crepeau AZ. Epilepsy and mortality after aneurysmal subarachnoid hemorrhage[J]. Neurology, 2017, 89(3): 222-223.
[16]
Watanabe Y, Uotani K, Nakazawa T, et al. Dual-energy direct bone removal CT angiography for evaluation of intracranial aneurysm or stenosis: comparison with conventional digital subtraction angiography[J]. Eur Radiol, 2009, 19(4): 1019-1024.
[1] 刘丹峰, 荚卫东. 基层医院开展腹腔镜肝脏手术的体会与思考[J]. 中华肝脏外科手术学电子杂志, 2023, 12(03): 263-266.
[2] 吴峻立, 苗毅. 胰腺神经内分泌肿瘤肝转移术前评估和外科治疗策略[J]. 中华肝脏外科手术学电子杂志, 2023, 12(01): 6-10.
[3] 王永楠, 王启弘, 殷杰, 欧春影. 锁孔开颅微血管减压术治疗前庭阵发症的初步研究[J]. 中华神经创伤外科电子杂志, 2023, 09(01): 43-47.
[4] 任鸿翔, 张黎, 张瑜廉, 刘学来, 于炎冰. 脑干听觉诱发电位在面肌痉挛显微血管减压术中的应用价值[J]. 中华神经创伤外科电子杂志, 2022, 08(02): 87-91.
[5] 樊晓彤, 闫峰, 王亚明. 立体定向机器人辅助经皮穿刺半月神经节球囊扩张压迫术[J]. 中华脑科疾病与康复杂志(电子版), 2023, 13(03): 191-192.
[6] 中国医师协会功能神经外科专家委员会, 世界华人神经外科协会功能神经外科专家委员会, 中国研究型医院学会神经外科学专业委员会, 中华医学会神经外科分会功能神经外科学组. 经皮球囊压迫术治疗三叉神经痛中国专家共识[J]. 中华脑科疾病与康复杂志(电子版), 2022, 12(05): 260-268.
[7] 李岩峰, 马逸. 经皮穿刺球囊压迫术治疗三叉神经痛在中国的现状与展望[J]. 中华脑科疾病与康复杂志(电子版), 2022, 12(04): 193-195.
[8] 王晶, 种玉龙, 姜成荣, 陆天宇, 戴宇翔, 梁维邦. 悬吊责任动脉技术治疗面肌痉挛的临床分析[J]. 中华脑科疾病与康复杂志(电子版), 2021, 11(05): 277-281.
[9] 王柏嵊, 张黎, 于炎冰. 面肌痉挛病因学的研究进展[J]. 中华脑科疾病与康复杂志(电子版), 2021, 11(04): 246-248.
[10] 姜成荣, 徐武, 种玉龙, 王晶, 周璐, 梁维邦. 三叉神经痛显微血管减压术中岩静脉的分型及处理策略[J]. 中华脑科疾病与康复杂志(电子版), 2021, 11(04): 200-203.
[11] 徐武, 姜成荣, 梁维邦. 卵圆孔形态和外口面积对半月神经节球囊压迫术的影响[J]. 中华脑科疾病与康复杂志(电子版), 2021, 11(04): 196-199.
[12] 吕晓波, 樊鹏飞, 景斐华, 文华波, 张晓强, 孟雅婷. 低张气充盈法多层螺旋CT增强扫描在胃部病变内镜治疗术前的评估价值[J]. 中华消化病与影像杂志(电子版), 2022, 12(03): 150-153.
[13] 高山, 董有静. 老年外科患者虚弱研究进展[J]. 中华临床医师杂志(电子版), 2023, 17(03): 343-348.
[14] 蒋亦林, 伍刚, 刘波, 沈洁, 刘如恩. 继发性三叉神经痛诊疗策略[J]. 中华临床医师杂志(电子版), 2022, 16(07): 643-646.
[15] 史鹏飞, 王常伟, 郭亚洲, 刘霄, 李锴, 刘禹, 何兵, 赵余涛, 刘德中. 经皮穿刺球囊压迫与显微血管减压术治疗老年人三叉神经痛的疗效及安全性[J]. 中华脑血管病杂志(电子版), 2022, 16(04): 258-262.
阅读次数
全文


摘要