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中华脑科疾病与康复杂志(电子版)

中华脑科疾病与康复杂志(电子版) ›› 2024, Vol. 14 ›› Issue (03) : 182 -186. doi: 10.3877/cma.j.issn.2095-123X.2024.03.010

综述

重复经颅磁刺激治疗脑卒中后中枢性疼痛的研究进展
武继敏1, 袁春雨1, 王鲁佳1, 陈伟霞2, 李晓东2, 马丽虹1,†()   
  1. 1. 250014　济南，山东中医药大学康复医学院
    2. 272000　济宁市第一人民医院康复科
  • 收稿日期:2023-11-18 出版日期:2024-06-15
  • 通信作者: 马丽虹

Research progress on repetitive transcranial magnetic stimulation in the treatment of central pain after stroke

Jimin Wu1, Chunyu Yuan1, Lujia Wang1, Weixia Chen2, Xiaodong Li2, Lihong Ma1,†()   

  1. 1. School of Rehabilitation Medicine, Shandong University of Traditional Chinese Medicine, Ji'nan 250014, China
    2. Department of Rehabilitation, the First People's Hospital of Jining City, Jining 272000, China
  • Received:2023-11-18 Published:2024-06-15
  • Corresponding author: Lihong Ma
  • Supported by:
    Shandong University of Chinese Medicine 2020 teaching reform team project(School education 2020-14-38)
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武继敏, 袁春雨, 王鲁佳, 陈伟霞, 李晓东, 马丽虹. 重复经颅磁刺激治疗脑卒中后中枢性疼痛的研究进展[J]. 中华脑科疾病与康复杂志(电子版), 2024, 14(03): 182-186.

Jimin Wu, Chunyu Yuan, Lujia Wang, Weixia Chen, Xiaodong Li, Lihong Ma. Research progress on repetitive transcranial magnetic stimulation in the treatment of central pain after stroke[J]. Chinese Journal of Brain Diseases and Rehabilitation(Electronic Edition), 2024, 14(03): 182-186.

脑卒中后中枢性疼痛（CPSP）作为一种情绪上的令人不快的主观感受，主要表现为连续或阵发性疼痛，以及刺激患肢后出现的诱发性疼痛，严重影响了患者康复过程中的整体功能恢复及生存质量。目前临床上常用抗抑郁及抗惊厥药物治疗CPSP，疗效较佳，但是长期服用此类药物容易产生依赖性和不良反应，而重复经颅磁刺激（rTMS）对CPSP有一定的改善作用。本文围绕rTMS治疗CPSP的研究进展进行综述，以期为脑卒中患者的康复治疗提供相关理论依据。

关键词: 脑卒中后中枢性疼痛, 重复经颅磁刺激, 机制, 研究进展

Central post-stroke pain (CPSP) is an unpleasant emotional subjective sensation that is mainly manifested as continuous or paroxysmal pain, as well as provoked pain after stimulation of the affected limb. CPSP seriously affects the overall functional recovery and quality of life of patients during rehabilitation. At present, antidepressants and anticonvulsants are often used in clinical practice to treat CPSP, with good therapeutic effects. However, long-term use of drugs can easily lead to dependence and adverse reactions, and repeated transcranial magnetic stimulation (rTMS) has a certain improvement effect on CPSP. This article reviews the research progress of rTMS in CPSP, in order to provide relevant theoretical basis for the rehabilitation treatment of stroke patients.

Key words: Central post-stroke pain, Repetitive transcranial magnetic stimulation, Mechanism, Research progress
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