Effect of closed-loop brain computer interface training based on imagination therapy on upper limb function of patients with hemiplegia after stroke

doi:10.3877/cma.j.issn.2095-123X.2022.06.008

Abstract

Abstract:

Objective

To explore the effect of closed-loop brain computer interface training based on imagination therapy on upper limb function of patients with hemiplegia after stroke.

Methods

Fifty-six patients with post-stroke hemiplegia admitted to rehabilitation department of Xuzhou Rehabilitation Hospital from February 2020 to May 2021 were divided into 2 groups according to the random number table, 28 patients in each group. The control group received routine rehabilitation training, while the observation group received closed-loop brain computer interface training based on imagination therapy. The Fugl-Meyer assessment upper extreme (FMA-UE), motor assessment scale (MAS), modified Barthel index (MBI) and motor status scale (MSS) were used to evaluate the upper limb motor function and activities of daily living of the 2 groups before treatment, 2 and 4 weeks after treatment.

Results

The FMA-UE, MAS, MBI and MSS scores of the two groups were analyzed by repeated measurement of variance, and the differences were statistically significant (P<0.05). After 2 and 4 weeks of treatment, the scores of FMA-UE, MBI and MSS in the 2 groups increased step by step, and the score of MAS decreased step by step (P<0.05). After 2 and 4 weeks of treatment, the scores of FMA-UE, MBI and MSS in the observation group were higher than those in the control group (P<0.05), and the scores of MAS were lower than that in the control group (P<0.05).

Conclusion

The closed-loop brain computer interface training based on imagination therapy can significantly improve the upper limb motor ability and muscle function of patients with hemiplegia after stroke, and improve the ability of daily activities.

Key words: Imagination therapy, Closed-loop brain computer interface, Stroke, Hemiplegia, Upper limb function

Li Zhang, Ming Zhang, Xiufang Zhang, Jingjie Zhou, Mengmeng Cen, Yanqiu Yuan, Xiuqing Zhu. Effect of closed-loop brain computer interface training based on imagination therapy on upper limb function of patients with hemiplegia after stroke[J]. Chinese Journal of Brain Diseases and Rehabilitation(Electronic Edition), 2022, 12(06): 360-364.

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References 18

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项目		对照组（n=28）	观察组（n=28）	χ²/t/U值	P值
性别[例（%）]				0.072	0.788
	男	12（42.86）	13（46.43）
	女	16（57.14）	15（53.57）
年龄（岁，Mean±SD）		53.28±2.15	52.46±2.23	1.401	0.167
病程[月，M（P₂₅，P₇₅）]		2.15（1.49，2.90）	2.19（1.05，3.20）	0.110	0.673
病变性质[例（%）]				0.311	0.577
	脑出血	11（39.29）	9（32.14）
	脑梗死	17（60.71）	19（67.86）
病变部位[例（%）]				0.381	0.537
	部分前循环	22（78.57）	20（71.43）
	后循环	6（21.43）	8（28.57）
利手[例（%）]				0.583	0.445
	左	3（10.71）	5（17.86）
	右	25（89.29）	23（82.14）
MMSE评分（分，Mean±SD）		27.38±0.51	27.42±0.46	0.308	0.759

项目		对照组（n=28）	观察组（n=28）	χ²/t/U值	P值
性别[例（%）]				0.072	0.788
	男	12（42.86）	13（46.43）
	女	16（57.14）	15（53.57）
年龄（岁，Mean±SD）		53.28±2.15	52.46±2.23	1.401	0.167
病程[月，M（P₂₅，P₇₅）]		2.15（1.49，2.90）	2.19（1.05，3.20）	0.110	0.673
病变性质[例（%）]				0.311	0.577
	脑出血	11（39.29）	9（32.14）
	脑梗死	17（60.71）	19（67.86）
病变部位[例（%）]				0.381	0.537
	部分前循环	22（78.57）	20（71.43）
	后循环	6（21.43）	8（28.57）
利手[例（%）]				0.583	0.445
	左	3（10.71）	5（17.86）
	右	25（89.29）	23（82.14）
MMSE评分（分，Mean±SD）		27.38±0.51	27.42±0.46	0.308	0.759

组别	例数	治疗前	治疗2周后	治疗4周后	F值	P值
观察组	28	21.79±2.35	32.82±2.65^a	41.68±2.83^ab	405.802	<0.001
对照组	28	22.17±2.29	30.69±2.71^a	38.61±2.77^ab	280.255	<0.001
t值		0.613	2.974	4.102
P值		0.543	0.004	<0.001

组别	例数	治疗前	治疗2周后	治疗4周后	F值	P值
观察组	28	21.79±2.35	32.82±2.65^a	41.68±2.83^ab	405.802	<0.001
对照组	28	22.17±2.29	30.69±2.71^a	38.61±2.77^ab	280.255	<0.001
t值		0.613	2.974	4.102
P值		0.543	0.004	<0.001

组别	例数	治疗前	治疗2周后	治疗4周后	F值	P值
观察组	28	4.78±0.45	3.39±0.43^a	2.32±0.22^ab	293.255	<0.001
对照组	28	4.73±0.49	3.65±0.45^a	2.61±0.28^ab	181.178	<0.001
t值		0.398	2.210	4.309
P值		0.692	0.031	<0.001

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