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中华脑科疾病与康复杂志(电子版)

中华脑科疾病与康复杂志(电子版) ›› 2022, Vol. 12 ›› Issue (02) : 115 -119. doi: 10.3877/cma.j.issn.2095-123X.2022.02.010

综述

动脉瘤性蛛网膜下腔出血后认知功能障碍的研究进展
李文虎1, 付帅2, 武玉亮1, 王磊1, 孔凡强1, 陈卫光1, 边玉松1, 陈永安1, 丛大伟3,†()   
  1. 1. 264000　烟台，青岛大学附属烟台毓璜顶医院急诊外科
    2. 264000　烟台，青岛大学附属烟台毓璜顶医院病案信息科
    3. 264100　烟台，滨州医学院烟台附属医院神经外科
  • 收稿日期:2021-12-20 出版日期:2022-04-15
  • 通信作者: 丛大伟

Research progress of cognitive dysfunction after aneurysmal subarachnoid hemorrhage

Wenhu Li1, Shuai Fu2, Yuliang Wu1, Lei Wang1, Fanqiang Kong1, Weiguang Chen1, Yusong Bian1, Yongan Chen1, Dawei Cong3,†()   

  1. 1. Department of Emergency Neurosurgery, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai 264000, China
    2. Department of Medical Record Information, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai 264000, China
    3. Department of Neurosurgery, Yantai Affiliated Hospital of Binzhou Medical University, Yantai 264100, China
  • Received:2021-12-20 Published:2022-04-15
  • Corresponding author: Dawei Cong
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引用本文：

李文虎, 付帅, 武玉亮, 王磊, 孔凡强, 陈卫光, 边玉松, 陈永安, 丛大伟. 动脉瘤性蛛网膜下腔出血后认知功能障碍的研究进展[J]. 中华脑科疾病与康复杂志(电子版), 2022, 12(02): 115-119.

Wenhu Li, Shuai Fu, Yuliang Wu, Lei Wang, Fanqiang Kong, Weiguang Chen, Yusong Bian, Yongan Chen, Dawei Cong. Research progress of cognitive dysfunction after aneurysmal subarachnoid hemorrhage[J]. Chinese Journal of Brain Diseases and Rehabilitation(Electronic Edition), 2022, 12(02): 115-119.

动脉瘤性蛛网膜下腔出血（aSAH）的发病率、致残率、致死率高，虽大多数患者可达到临床治愈，但仍有部分遗留长期认知功能障碍，临床隐匿，不易察觉。早期使用神经心理学量表和神经电生理检查进行认知功能障碍的评估至关重要。目前认为认知功能障碍的发病机制和严重程度可能与早期脑损伤、脑血管痉挛、迟发性脑缺血等因素有关，主要以预防、药物和康复治疗为主，且早期康复治疗能改善认知功能。脑网络组学在神经外科的应用可促进aSAH后认知功能障碍的研究与进展。本文主要围绕aSAH后认知功能障碍的研究进展作一综述。

关键词: 颅内动脉瘤, 蛛网膜下腔出血, 认知功能障碍, 脑网络组学

Aneurysmal subarachnoid hemorrhage (aSAH) has high morbidity, mortality and disability rates. Although most patients can be cured clinically, there are still some patients with long-term cognitive dysfunction, which is clinically hidden and difficult to detect. Early assessment of cognitive impairment using neuropsychological scales and neuroelectrophysiological tests is critical. It is currently believed that the pathogenesis and severity of cognitive impairment may be related to early brain injury, cerebral vasospasm, delayed cerebral ischemia and other factors. Mainly based on prevention, drugs and rehabilitation treatment, and rehabilitation treatment as soon as possible can improve cognitive function. The application of brain network omics in neurosurgery can promote the research and progress of cognitive dysfunction after aSAH. This paper reviews the research progress of cognitive impairment after aSAH.

Key words: Intracranial aneurysm, Subarachnoid hemorrhage, Cognitive dysfunction, Brain netomics
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