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中华脑科疾病与康复杂志(电子版) ›› 2019, Vol. 09 ›› Issue (03) : 181 -184. doi: 10.3877/cma.j.issn.2095-123X.2019.03.013

所属专题： 文献；

综述

经颅直流电刺激神经调控治疗慢性意识障碍的现状及前景
郭永坤1, 戴宜武2, 刘春颖1,†(), 白洋3, 何江弘2, 张辉1   
  1. 1. 450007　郑州，郑州大学附属郑州中心医院神经外科
    2. 100700　北京，解放军总医院第七医学中心神经外科
    3. 311121　杭州，杭州师范大学基础医学院
  • 收稿日期:2018-10-11 出版日期:2019-06-15
  • 通信作者: 刘春颖
  • 基金资助:
    广东省重点领域研发计划项目(2018B030339001); 河南省高等学校重点科研项目(19A320041；18B310037)

Current status of transcranial direct current stimulation neuromodulation therapy for chronic disorders of consciousness

Yongkun Guo1, Yiwu Dai2, Chunying Liu1,†(), Yang Bai3, Jianghong He2, Hui Zhang1   

  1. 1. Department of Neurosurgery, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou 450007, China
    2. Department of Neurosurgery, The 7th Medical Center of the Chinese People’s Liberation Army General Hospital, Beijing 100700, China
    3. School of Basic Medical Science, Hangzhou Normal University, Hangzhou 311121, China
  • Received:2018-10-11 Published:2019-06-15
  • Corresponding author: Chunying Liu
  • About author:
    Corresponding author: Liu Chunying, Email:
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引用本文：

郭永坤, 戴宜武, 刘春颖, 白洋, 何江弘, 张辉. 经颅直流电刺激神经调控治疗慢性意识障碍的现状及前景[J/OL]. 中华脑科疾病与康复杂志(电子版), 2019, 09(03): 181-184.

Yongkun Guo, Yiwu Dai, Chunying Liu, Yang Bai, Jianghong He, Hui Zhang. Current status of transcranial direct current stimulation neuromodulation therapy for chronic disorders of consciousness[J/OL]. Chinese Journal of Brain Diseases and Rehabilitation(Electronic Edition), 2019, 09(03): 181-184.

严重脑损伤导致的意识障碍（DOC），目前尚未有基于循证医学依据的指南。经颅直流电刺激（tDCS）是神经调控治疗DOC非常有前景的技术，已成为昏迷促醒治疗研究的热点。本文围绕tDCS的治疗效果、刺激参数、刺激靶点及促醒机制等方面的研究现状展开综述。

关键词: 经颅直流电刺激, 意识障碍, 脑电图, 核磁共振

Patients after severe brain injuries would be disorders of consciousness (DOC), but evidence-based guidelines on the treatment of DOC patients are not currently available. Transcranial direct current stimulation (tDCS) has been reported to be a promising technique for consciousness improvement for patients with DOC, becoming a new hotspot in the research field. This article reviews the current research status of tDCS in terms of therapeutic effect, stimulation parameters, stimulation targets and the arousal mechanism.

Key words: Transcranial direct current stimulation, Disorders of consciousness, Electroencephalography, Magnetic resonance imaging
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