脑电非线性分析在卒中后意识障碍的研究进展

doi:10.3877/cma.j.issn.2095-123X.2023.03.010

意识障碍（DOC）是脑卒中等疾病的严重并发症，我国医疗体系正在面临DOC患者数量增加带来的医疗及伦理问题。近年来，昏迷促醒医学领域发展迅速，但目前对DOC患者的意识评定主要依靠临床行为学量表等主观手段，缺乏客观准确的检查方法。脑电非线性分析是一项新颖电生理检查，将非线性动力学分析方法与脑电图结合，具有高时间分辨率、无创、便携等优势。本文围绕脑电非线性分析对卒中后DOC患者的意识水平、意识恢复过程、预后及康复疗效的评定作用进行综述，为DOC多模态评估及促醒体系的发展提供帮助。

关键词: 意识障碍, 脑卒中, 脑电图, 非线性动力学

Disorders of consciousness (DOC) is a serious complication of stroke and other diseases, China's medical system is facing medical and ethical problems brought about by the increasing number of DOC patients. In recent years, the field of coma-arousal medicine has developed rapidly, and the current assessment of DOC patients' consciousness mainly relies on subjective means, such as clinical behavioral scales, but lack of examination methods which is objective and accurate. Electroencephalogram (EEG) non-linear analysis is a novel electrophysiological examination, which combines nonlinear dynamics analysis with EEG. It has the advantages of high temporal resolution, non-invasive, portable and so on. This paper reviews the role of EEG non-linear analysis in evaluating the level of consciousness, the process of recovering from consciousness, prognosis and the efficacy of rehabilitation in patients with DOC after stroke, and provides assistance for the development of multimodal assessment and treatment system of DOC.

Key words: Disorder of consciousness, Stroke, Electroencephalogram, Non-linear dynamics

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Research progress of EEG non-linear analysis in disorders of consciousness

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Research progress of EEG non-linear analysis in disorders of consciousness