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中华脑科疾病与康复杂志(电子版) ›› 2021, Vol. 11 ›› Issue (02) : 92 -96. doi: 10.3877/cma.j.issn.2095-123X.2021.02.006

临床研究

经顶枕皮层入路显微外科手术治疗侧脑室三角区脑膜瘤的效果分析
林建浩1, 李业海1, 叶景1, 黄佛宝1, 何桂录1, 李俏1, 张良1,()   
  1. 1. 510510 广州,广东三九脑科医院神经外一科
  • 收稿日期:2021-01-31 出版日期:2021-04-15
  • 通信作者: 张良
  • 基金资助:
    广州市科技计划项目(202002030309)

Microsurgery of trigonal meningioma of the lateral ventricle through parietooccipital cortex approach

Jianhao Lin1, Yehai Li1, Jing Ye1, Fobao Huang1, Guilu He1, Qiao Li1, Liang Zhang1,()   

  1. 1. The First Department of Neurosurgery, Guangdong 999 Brain Hospital, Guangzhou 510510, China
  • Received:2021-01-31 Published:2021-04-15
  • Corresponding author: Liang Zhang
引用本文:

林建浩, 李业海, 叶景, 黄佛宝, 何桂录, 李俏, 张良. 经顶枕皮层入路显微外科手术治疗侧脑室三角区脑膜瘤的效果分析[J]. 中华脑科疾病与康复杂志(电子版), 2021, 11(02): 92-96.

Jianhao Lin, Yehai Li, Jing Ye, Fobao Huang, Guilu He, Qiao Li, Liang Zhang. Microsurgery of trigonal meningioma of the lateral ventricle through parietooccipital cortex approach[J]. Chinese Journal of Brain Diseases and Rehabilitation(Electronic Edition), 2021, 11(02): 92-96.

目的

探讨经顶枕皮层入路显微手术切除侧脑室三角区脑膜瘤的手术方法、效果及并发症防治。

方法

回顾性分析广东三九脑科医院自2017年3月至2020年9月行经顶枕皮层入路手术切除的26例侧脑室三角区脑膜瘤的临床资料,观察患者手术切除程度、病理结果、术后并发症、Karnofsky评分及复发情况。

结果

26例患者的脑膜瘤均完全切除,无死亡患者(1例患者因入院时脑疝,术后放弃治疗)。术后病理检查均证实为脑膜瘤,WHO Ⅰ级19例、WHO Ⅱ级7例(非典型脑膜瘤6例,脊索样脑膜瘤1例)。术后10例患者出现新发视野缺损,无1患者出现皮质盲,6例患者出现孤立颞角(1例行造瘘,3例行脑室腹腔分流,2例为静止性孤立颞角未行处理),1例患者出现硬膜外血肿,2例患者出现一过性肌力下降。所有肿瘤均达到完全切除,病理报告提示为WHO Ⅱ级的患者均常规行放射治疗,术后随访0.5~3年复发2例,均为WHO Ⅱ级患者。

结论

合适的手术入路、充分地术前及术中准备,丰富的显微手术经验及技巧在侧脑室三角区脑膜瘤手术中可有效减少并发症的发生。

Objective

To investigate the surgical method, effect and complications of surgical resection of trigonal meningiomas through parietooccipital cortex approach.

Methods

The clinical data and 26 patients with lateral ventricle trigona meningiomas who underwent surgery through parietooccipital cortex approach from March 2017 to September 2020 were retrospectively analyzed. The extent of surgical resection, pathological results, postoperative complications, Karnofsky score and recurrence were observed.

Results

Meningiomas were completely resected in all patients, and there was no death (1 patient gave up treatment after surgery). Postoperative pathological exams were confirmed as meningioma, among them, WHO Ⅰ in 19 cases, WHO Ⅱ in 7 cases (6 cases with atypical meningioma, 1 case with Chordoid meningioma). Postoperatively, 10 patients developed new visual defects, no patient developed cortical blindness, 6 patients developed isolated temporal horn (1 with an ostomy, 3 with a ventriculoperitoneal shunt, and 2 with spontaneous remission), 1 patient developed epidural hematoma, and 2 patients experienced transient muscle strength loss. All tumors achieved gross total resection. Patients with WHO Ⅱ were routinely treated with radiotherapy, and 2 of them with recurrence by following up 3 years.

Conclusion

Appropriate surgical approach, adequate preoperative and intraoperative preparation, and rich surgical experience and skills can effectively reduce complications in the operation of lateral ventricle trigonum meningioma.

表1 26例侧脑室三角区脑膜瘤患者的一般资料
表2 26例侧脑室三角区脑膜瘤患者的术后资料
序号 切除程度 病理报告 放射治疗 复发 KPS评分(分)
1 全切除 合体细胞型脑膜瘤,WHO Ⅰ级 80
2 全切除 纤维细胞型脑膜瘤,WHO Ⅰ级 100
3 全切除 纤维细胞型脑膜瘤,WHO Ⅰ级 50
4 全切除 纤维细胞型脑膜瘤,WHO Ⅰ级 80
5 全切除 纤维细胞型脑膜瘤,WHO Ⅰ级 90
6 全切除 纤维细胞型脑膜瘤,WHO Ⅰ级 100
7 全切除 富于淋巴细胞浆细胞型脑膜瘤,WHO Ⅰ级 80
8 全切除 纤维细胞型脑膜瘤,WHO Ⅰ级 100
9 全切除 非典型脑膜瘤,WHO Ⅱ级 80
10 全切除 血管瘤型脑膜瘤,WHO Ⅰ级 90
11 全切除 纤维细胞型脑膜瘤,WHO Ⅰ级 100
12 全切除 纤维型脑膜瘤,WHO Ⅰ级 100
13 全切除 脊索样脑膜瘤,WHO Ⅱ级 90
14 全切除 过渡型脑膜瘤,WHO Ⅰ级 100
15 全切除 非典型脑膜瘤,WHO Ⅱ级 80
16 全切除 非典型脑膜瘤,WHO Ⅱ级 100
17 全切除 过渡型脑膜瘤,WHO Ⅰ级 80
18 全切除 非典型脑膜瘤,WHO Ⅱ级 100
19 全切除 非典型脑膜瘤,WHO Ⅱ级 90
20 全切除 过渡型脑膜瘤,WHO Ⅰ级 100
21 全切除 过渡型脑膜瘤,WHO Ⅰ级 90
22 全切除 过渡型脑膜瘤,WHO Ⅰ级 90
23 全切除 纤维型脑膜瘤,WHO Ⅰ级 100
24 全切除 过渡型脑膜瘤,WHO Ⅰ级 100
25 全切除 过渡型脑膜瘤,WHO Ⅰ级 90
26 全切除 非典型脑膜瘤,WHO Ⅱ级 70
图1 典型侧脑室三角区脑膜瘤患者术前术后影像学资料
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