脑卒中已成为危害人类身体健康的重大神经系统疾病，救治的关键是解决在"1 h黄金时间"内即时诊断与治疗的"瓶颈"问题。2022年《欧洲卒中组织（ESO）移动卒中单元院前卒中管理指南》发表，这是全球第1个移动卒中单元（MSU）院前卒中管理指南。指南建议：对于确诊的急性缺血性脑卒中患者，使用MSU进行院前管理可改善其临床功能效果，提高静脉溶栓治疗率，缩短开始溶栓治疗时间。对于颅内出血患者，使用MSU进行院前管理可增加直接分配运送到三级医疗卒中中心的患者比例，而无需担心短期死亡率。对类卒中患者使用MSU管理没有发现相关安全问题。本文就该指南进行解读，以更好地指导临床实践。

Stroke has become a major nervous system disease that endangers human health. The key to cure is to solve the "bottleneck" problem of immediate diagnosis and treatment within the "1 h golden time" . In 2022, the "European Stroke Organisation (ESO) guidelines on mobile stroke units for prehospital stroke management" was published, which is the first mobile stroke unit (MSU) prehospital stroke management guide in the world. Guideline recommendations: For patients with confirmed acute ischemic stroke, using MSU for prehospital management can improve their clinical function, increase the rate of IVT treatment, and shorten the time to start thrombolytic therapy. For patients with intracranial hemorrhage, using MSU for prehospital management can increase the proportion of patients directly assigned to tertiary medical stroke centers without concern about short-term mortality. No relevant safety concerns were identified with MSU management in suspected stroke patients. This article will interpret this guideline to better guide clinical practice.