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中华脑科疾病与康复杂志(电子版) ›› 2023, Vol. 13 ›› Issue (06) : 364 -368. doi: 10.3877/cma.j.issn.2095-123X.2023.06.008

短篇论著

乙状窦后入路听神经瘤术中内听道的个体化处理
尹浩扬, 辛运, 蒋涛, 吴越, 程崇杰, 夏海坚, 张文韬, 孙晓川, 唐文渊, 徐胜生, 钟东()   
  1. 400016 重庆,重庆医科大学附属第一医院神经外科
    400016 重庆,重庆医科大学附属第一医院放射科
  • 收稿日期:2023-03-13 出版日期:2023-12-15
  • 通信作者: 钟东

Optimization strategy for individualized management of the internal auditory canal during retrosigmoid approach for acoustic neuroma

Haoyang Yin, Yun Xin, Tao Jiang, Yue Wu, Chongjie Cheng, Haijian Xia, Wentao Zhang, Xiaochuan Sun, Wenyuan Tang, Shengsheng Xu, Dong Zhong()   

  1. Department of Neurosurgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China
    Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China
  • Received:2023-03-13 Published:2023-12-15
  • Corresponding author: Dong Zhong
引用本文:

尹浩扬, 辛运, 蒋涛, 吴越, 程崇杰, 夏海坚, 张文韬, 孙晓川, 唐文渊, 徐胜生, 钟东. 乙状窦后入路听神经瘤术中内听道的个体化处理[J]. 中华脑科疾病与康复杂志(电子版), 2023, 13(06): 364-368.

Haoyang Yin, Yun Xin, Tao Jiang, Yue Wu, Chongjie Cheng, Haijian Xia, Wentao Zhang, Xiaochuan Sun, Wenyuan Tang, Shengsheng Xu, Dong Zhong. Optimization strategy for individualized management of the internal auditory canal during retrosigmoid approach for acoustic neuroma[J]. Chinese Journal of Brain Diseases and Rehabilitation(Electronic Edition), 2023, 13(06): 364-368.

目的

探讨显微神经外科手术处理内听道内的个体化策略,以达到患者利益最大化。

方法

回顾性分析重庆医科大学附属第一医院神经外科自2021年9月至2022年8月行神经内镜辅助经枕下乙状窦后入路显微外科手术治疗的27例听神经瘤患者的临床资料。根据患者肿瘤长入内听道的程度及身体基础情况,分为内听道磨开组(18例)和掏刮组(9例),比较2组患者的手术时间、肿瘤的切除程度、面神经的保留以及术后感染情况。

结果

内听道磨开组中肿瘤完全切除9例,近全切除7例,次全切除2例;掏刮组中肿瘤完全切除2例,近全切除5例,次全切除2例;2组患者的近全及以上切除率比较,差异无统计学意义(P>0.05)。术中镜下观察所有患者面神经均得到解剖保留。2组患者的手术时间和住院费用比较,差异均有统计学意义(P<0.05)。内听道磨开组患者术后3个月House-Brackmann(H-B)Ⅰ~Ⅱ级9例,Ⅲ级7例,Ⅳ级2例;掏刮组患者术后3个月H-BⅠ~Ⅱ级5例,Ⅲ级4例,Ⅳ级0例。术后发生颅内感染4例,其中内听道磨开组3例,掏刮组1例。

结论

相对于内听道磨开法,掏刮法的手术耗时更短,术后并发症发生率相对更低,患者的住院天数和医疗费用更少。通过精准的术前评估,对合适的患者采用掏刮法处理内听道内肿瘤更利于提高疗效。

Objective

To explore the individualized strategy of micro neurosurgery in the internal auditory canal (IAC) in order to maximize the benefits of patients.

Methods

A retrospective analysis was conducted on the clinical data of 27 patients with acoustic neuroma treated by neuroendoscopy-assisted microsurgery via suboccipital retrosigmoid approach from September 2021 to August 2022 in the Neurosurgery Department of The First Hospital of Chongqing Medical University. According to the extent of tumor growth into the internal auditory canal and the physical foundation of the patients, the patient were divided into the drilling open IAC group (18 cases) and the scraping group (9 cases). The operative time, the degree of tumor resection, the preservation of the facial nerve, and the control of postoperative infections were compared between the two groups.

Results

Nine patients had complete resection of the tumor by drilling open the posterior superior wall of the internal auditory canal, 7 patients had near-total resection, and 2 patients had subtotal resection (tight adhesion to the brainstem). Two patients had complete resection of tumor by scraping method, 5 patients had near-total resection and 2 patients had subtotal resection. There was no statistically significant difference in the near-total and above resection rates between the 2 groups of patients (P>0.05). Intraoperative microscopic observation of the facial nerve was anatomically preserved in all patients. Comparing the operation time and hospitalization expenses between the two groups of patients, the differences were statistically significant (P<0.05). According to the House-Brackmann (H-B) facial nerve function classification, the facial nerve function in the three-month postoperative period was grade Ⅰ-Ⅱ in 9 patients, grade Ⅲ in 7 patients, and grade Ⅳ in 2 patients by the drilling method, and grade Ⅰ-Ⅱ in 5 patients, grade Ⅲ in 4 patients, and grade Ⅳ in 0 patients by the scraping method. The Intracranial infection occurred in 4 cases after surgery, including 3 cases in the drilling open IAC group and 1 case in the scraping group.

Conclusion

The scraping method is less time-consuming and has a lower postoperative complication rate than the drilling method, and the number of days of hospitalization and medical costs for patients with scraping are reduced accordingly. Through accurate preoperative evaluation, it is more beneficial to improve the curative effect of appropriate patients to use the scraping method to treat tumors in the internal auditory canal.

表1 2组患者的基线资料比较
Tab.1 Comparison of baseline data of patients in 2 groups
表2 内听道磨开组与掏刮组患者临床疗效比较
Tab.2 Comparison of clinical effectiveness between the drilling open IAC group and the scraping group
[1]
Paldor I, Chen AS, Kaye AH. Growth rate of vestibular schwannoma[J]. J Clin Neurosci, 2016, 32: 1-8. DOI: 10.1016/j.jocn.2016.05.003.
[2]
Goldbrunner R, Weller M, Regis J, et al. EANO guideline on the diagnosis and treatment of vestibular schwannoma[J]. Neuro Oncol, 2020, 22(1): 31-45. DOI: 10.1093/neuonc/noz153.
[3]
Breshears JD, Morshed RA, Molinaro AM, et al. Residual tumor volume and location predict progression after primary subtotal resection of sporadic vestibular schwannomas: a retrospective volumetric study[J]. Neurosurgery, 2020, 86(3): 410-416. DOI: 10.1093/neuros/nyz200.
[4]
Dubernard X, Kleiber JC, Makeieff M, et al. Drilling and control of the internal auditory canal by fixed endoscope[J]. Eur Ann Otorhinolaryngol Head Neck Dis, 2019, 136(1): 37-39. DOI: 10.1016/j.anorl.2018.09.005.
[5]
陈贵杰,钟东,唐文渊,等.听神经瘤显微神经外科手术中内听道后上壁的处理及临床疗效分析[J].第三军医大学学报, 2013, 35(16): 1740-1743. DOI: 10.16016/j.1000-5404.2013.16.027.
[6]
谷速杰,李俊,李闪闪,等.听神经瘤切除术中内听道内肿瘤的个体化处理[J].中国临床神经外科杂志, 2019, 24(2): 69-71. DOI: 10.13798/j.issn.1009-153X.2019.02.002.
[7]
Spielmann PM, Sillars H. Assessing the threshold for vestibular schwannoma resection and the behavior of residual tumor[J]. Otol Neurotol, 2013, 34(5): 935-938. DOI: 10.1097/MAO.0b013e31827de2ec.
[8]
杨军.听神经瘤治疗进展[J].中国现代神经疾病杂志, 2022, 22(12): 1011-1016. DOI: 10.3969/j.issn.1672-6731.2022.12.002.
[9]
舒凯,雷霆.听神经瘤术后残留及复发的相关因素[J].临床外科杂志, 2021, 29(10): 916-918. DOI: 10.3969/j.issn.1005-6483.2021.10.006.
[10]
Gupta A, Turel MK, Moorthy RK, et al. Treatment outcomes and follow-up compliance after less than total and total resection of vestibular schwannomas in 294 patients[J]. Neurol India, 2020, 68(6): 1351-1360. DOI: 10.4103/0028-3886.304069.
[11]
蒲珂,王宏,丁维亮,等.近全切除策略在听神经瘤手术中的应用及疗效分析[J].中华神经外科杂志, 2016, 32(1): 8-12. DOI: 10.3760/cma.j.issn.1001-2346.2016.01.003.
[12]
Carlson ML, Van Abel KM, Driscoll CL, et al. Magnetic resonance imaging surveillance following vestibular schwannoma resection[J]. Laryngoscope, 2012, 122(2): 378-388. DOI: 10.1002/lary.22411.
[13]
贺鹏,李冉,罗文凯,等.听神经瘤术后并发耳鸣及脑脊液漏的影响因素分析[J].天津医药, 2021, 49(6): 625-628. DOI: 10.11958/20202517.
[14]
郭致飞,赵兵,吴德俊,等.颅底肿瘤开颅手术后颅内感染相关危险因素分析[J].中国现代神经疾病杂志, 2021, 21(8): 659-664. DOI: 10.3969/j.issn.1672-6731.2021.08.008.
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