[1] |
Hashinmoto Y,Ito Y,Niikura T, et al. Mechanisms of neuroprotection by a novel factor humanin from Swedish mutant amyloid precursor protein[J]. Biochem Biophys Res Commun, 2001, 283(2):460-468.
|
[2] |
Sponne I,Fifre A,Koziel V, et al. Humanin rescues cortical neurons from prion-peptide-induced apoptosis[J]. Mol Cell Neurosci, 2004, 25(1):95-102.
|
[3] |
Tsukamoto E,Hashimoto Y,Kanekura K, et al. Characterization of the toxic mechanism triggered by Alzheime's amyloid-beta peptides via p75 neurotrophin receptor in neuronal hybrid cells [J]. J Neurosci Res, 2003, 73(5):627-636.
|
[4] |
Niikura T,Sidahmed E,Hirata-Fukae C, et al. A humanin derivative reduces amyloid Beta accumulation and ameliorates memory deficit in triple transgenic mice [J]. PLoS One, 2011, 6(1):e16259.
|
[5] |
Zhang W,Zhang W,Li Z, et al. S14G-humanin improves cognitive deficits and reduces amyloid pathology in the middle-aged APPswe/PS1dE9 mice[J]. Pharmacol Biochem Behav, 2012, 100(3):361-369.
|
[6] |
Matsuoka M,Hashimoto Y. Humanin and the receptors for humanin[J]. Mol Neurobiol, 2010, 41(1): 22-28.
|
[7] |
Oh YK,Bachar AR,Zacharias DG, et al. Humanin preserves endothelial function and prevents atherosclerotic plaque progression in hypercholesterolemic ApoE deficient mice[J]. Atherosclerosis, 2011, 219(1):65-73.
|
[8] |
Adi R. Bachar,Lea Scheffer,Andreas S, et al. Humanin is expressed in human vascular walls and has a cytoprotective effect against oxidized LDL-induced oxidative stress [J]. Caridovascular Research, 2010, 88(2):360-366.
|
[9] |
Kariya S,Takahashi N,Ooba NK, et al. Humanin inhibits cell death of serum-deprived PC12h cells [J]. Neuroreport, 2002, 13(6):903-907.
|
[10] |
Tajima H,Niikura T,Hashimoto Y,et al. Evidence for in vivo production of Humanin peptide, a neuroprotective factor against Alzheimer′s disease-related insults[J]. Neurosci Lett, 2002, 324(3):227-231.
|
[11] |
Niikura T,Yamada M,Chiba T, et al. Characterization of V642I-AβPP-induced cytotoxicity in primary neurons [J]. J Neurosci Res, 2004, 77(1):54-62.
|
[12] |
Hashimoto Y,Niikura T,Ito Y, et al. Detailed characterization of neuto-protection by a rescue factor humanin against various Alzheimer′s disease-relevant insults [J]. J Neurosci, 2001, 21(23):9235-9245.
|
[13] |
Chiba T,Yamada M,Hashimoto Y, et al. Development of a femtomolar-acting humanin derivative named colivelin by attaching activity-dependent neurotrophic factor to its N terminus: characterization of colivelin-mediated neuroprotection against Alzheimer′s disease-relevant insults in vitro and in vivo[J]. J Neurosci, 2005, 25(44):10252-10261.
|
[14] |
Yamagishi Y,Hashimoto Y,Niikura T, et al. Identification of essential amino acids in Humanin, a neuroprotective factor against Alzheimer′s disease-relevant insults [J]. Peptide, 2003, 24(4):585-595.
|
[15] |
Jung SS,Van Nostrand WE. Humanin rescues human cerebrovascular smooth muscle cells from Abeta-induced toxicity [J]. J Neurochem, 2003, 84(2):266-272.
|
[16] |
Mamiya T,Ukai M. [Gly(14)]-Humanin improved the learning and memory impairment induced by scopolamine in vivo[J]. Br J Pharmacol, 2001, 134(8):1597-1599.
|
[17] |
Tajima H,Kawasumi M,Chiba T, et al. A humanin derivative, S14G-HN, prevents amyloid-beta-induced memory impairment in mice [J]. J Neurosci Res, 2005, 79(5): 714-723.
|
[18] |
Yuan L,Han WN,Li SF, et al. [Gly14]-humanin protects against Aβ31-35-induced impairment of spatial learning and memory in rats[J]. Sheng Li Xue Bao, 2012, 64(6): 625-632.
|
[19] |
Bachar AR,Scheffer L,Schroeder AS, et al. Humanin is expressed in human vascular walls and has a cytoprotective effect against oxidized LDL-induced oxidative stress [J]. Cardiovasc Res, 2010, 88(2):360-366.
|
[20] |
Xu X,Chua CC,Gao J, et al. Humanin is a novel neuroprotective agent against stroke [J]. Stroke, 2006, 37(10):2613-2619.
|
[21] |
Chiba T,Yamada M,Sasabe J, et al. Colivelin prolongs survival of an ALS model mouse [J]. Biochem Biophys Res Commun, 2006, 343(3):793-798.
|
[22] |
Kuliawat R,Klein L,Gong Z, et al. Potent humanin analog increases glucose-stimulated insulin secretion through enhanced metabolism in the β cell [J]. FASEB J, 2013, 27(12):4890-4898.
|
[23] |
Hoang PT,Park P,Cobb LJ, et al. The neurosurvival factor Humanin inhibits beta-cell apoptosis via signal transducer and activator of transcription 3 activation and delays and ameliorates diabetes in nonbese diabetic mice [J]. Metabolism 2010, 59(3):343-349.
|
[24] |
Muzumdar RH,Huffman DM,Calvert JW, et al. Acute humanin therapy attenuates myocardial ischemia and reperfusion injury in mice[J]. Arterioscler Thromb Vasc Biol, 2010, 30(10):1940-1948.
|
[25] |
Lue Y,Swerdloff R,Liu Q, et al. Opposing roles of insulin-like growth factor bingding protein 3 and humanmin in the regulation of testicular germ cell apoptosis [J]. Endocrinology, 2010, 151(1):350-357.
|
[26] |
Zhao ST,Zhao L,Li JH, et al. Neuroprotective peptide humanin inhibits inflammatory response in astrocytes induced in lipopolysaccharide [J]. Neurochem Res, 2013, 38(3): 581-588.
|
[27] |
Eriksson E,Wicksrtom M,Perup LS, et al. Protective role of humanin on bortezomibinduced bone growth impairment in anti-cancer treatment [J]. J Natl Cancer Inst, 2014, 106(3):djt459.
|
[28] |
Cohen P. New role for the mitochondrial peptide humanin: Protective agent against chemotheraphy-induced side effects [J]. J Natl Cancer Inst, 2014, 106(3):dju006.
|
[29] |
Matsuoka M,Hashimoto Y,Aiso S, et al. Humanin and colivelin: neuronal-death-suppressing peptides for Alzheimer′s disease and amyotrophic lateral sclerosis [J]. CNS Drug Rev, 2006, 12(2):113-122.
|
[30] |
Hashimoto Y,Niikura T,Tajima H, et al. A rescue factor abolishing neuronal cell death by a wide pectrum of familial Alzheimer′s disease genes and Abeta [J]. Proc Natl Acad Sci USA, 2001, 98(11):6336-6341.
|
[31] |
Arakawa T,Hirano A,Shiraki K, et al. Advances in characterization of neuroprotective peptide, humanin [J]. Curr Med Chem, 2011, 18(36):5554-5563.
|
[32] |
Tsukamoto E,Kadowaki H,Nishitoh H,Yamagishi Y, et al. The cytoplasmic domain of Alzheimer′s amyloid-protein precursor causes sustained apoptosis signal-regulating kinase 1/c-Jun NH-terminal kinase-mediated neurotoxic signal via dimerization[J]. J Pharmacol Exp Ther, 2003, 306(3), 889-902.
|
[33] |
Le Y,Gong W,Tiffany HL, et al. Amyloid - activates a G-protein-coupled chemoattractant receptor, FPR-like-1[J]. J Neurosci, 2001, 21(2), RC123.
|
[34] |
Ying G,Iribarren P,Zhou Y,et al. Humanin, a newly identified neuroprotective factor, uses the G protein-coupled formylpeptide receptor-like-1 as a functional receptor[J]. J Immunol, 2004, 172(11): 7078-7085.
|
[35] |
Hashimoto Y,Kurita M,Aiso S, et al. Humanin inhibits neuronal cell death by interacting with a cytokine receptor complex or complexes involving CNTF receptor alpha/WSX-1/gp130[J]. Mol Biol Cell, 2009, 20(12):2864-2873.
|
[36] |
Hashimoto Y,Kurita M,Matsuoka M. Identification of soluble WSX-1 not as a dominant-negative but as an alternative functional subunit of a receptor for an anti-Alzheimer′s disease rescue factor Humanin [J]. Biochem Biophys Res Commun, 2009, 389(1):95-99.
|
[37] |
Yamada M,Chiba T,Sasabe J, et al. Nasal Colivelin treatment ameliorates memory impairment related to Alzheimer′s disease[J]. Neuropsychopharmacology, 2008, 33(8): 2020-2032.
|
[38] |
Guo B,Zhai D,Cabezas E, et al. Humanin peptide suppresses apoptosis by interfering with Bax activation [J]. Nature, 2003, 423(6938):456-461.
|
[39] |
Hashimoto Y,Tsuji O,Niikura T, et al. Involvement of cJun N-terminal kinase in amyloid precursor protein-mediated neuronal cell death[J]. J Neurochem, 2003, 84(4): 864-877.
|
[40] |
Niikura T,Hashimoto Y,Tajima H, et al. A tripartite motif protein TRIM11 binds and destabilizes Humanin, a neuroprotective peptide against Alzheimer′s disease relevant insults [J]. Eur J Neurosci, 2003, 17(6):1150-1158.
|
[41] |
Kariya S,Takahashi N,Hirano M, et al. Humanin improves impaired metabolic activity and prolongs survival of serum-deprived human lymphocytes [J]. Mol Cell Biochem, 2003, 254(1/2): 83-89.
|
[42] |
Yarchoan M,Xie SX,Kling MA, et al. Cerebrovascular atherosclerosis correlates with Alzheimer pathology in neurodegenerative dementias [J]. Brain, 2012, 135(12):3749-3756.
|
[43] |
Chi NF,Chien LN,Ku HL, et al. Alzheimer disease and risk of stroke: A population-based cohort study [J]. Neurology, 2013, 80(8):705-711.
|
[44] |
杨飞. 抗凋亡肽Humanin通过抑制高脂血症状态下血小板的高反应性缓解动脉粥样硬化的发展[D]. 苏州:苏州大学,2012:1-40.
|