Theta爆发式经颅磁刺激治疗卒中后失语的研究进展

doi:10.3877/cma.j.issn.2095-123X.2024.03.008

随着卒中发病率的不断上升，患病人群逐渐呈现年轻化趋势。卒中后语言功能障碍不仅会影响患者和他人的交流，而且会导致患者理解力下降、发音困难、情绪低落等，从而无法理解康复指令，难以配合康复训练，影响预后。Theta爆发式经颅磁刺激（TBS）作为一种新兴的经颅磁刺激模式，有助于卒中后失语患者语言能力的恢复，但其治疗方案却各不相同。本文围绕TBS的作用原理、不同刺激模式（如间歇性TBS和持续性TBS）的基本特征、改善失语的机制、治疗失语的不同刺激方案及目前国内外关于TBS治疗失语的相关研究所存在的局限性等方面展开综述，以期为卒中后失语的康复治疗提供新的临床参考和思路。

关键词: 卒中, Theta爆发式经颅磁刺激, 康复, 失语

Currently, the incidence of stroke is steadily increasing, and the patient population is gradually becoming younger. The resulting language impairments not only affect communication between patients and others, but also hinder the patient's understanding of recovery instructions due to decreased comprehension, speech difficulties, and emotional depression, making it challenging to cooperate with rehabilitation training. This, in turn, affects the overall prognosis of the patient. Theta burst stimulation (TBS), as an emerging transcranial magnetic stimulation modality, aids in the recovery of language abilities in post-stroke aphasia patients, but the treatment protocols vary widely. This article provides a comprehensive review of the principles of TBS, the basic characteristics of different stimulation modes (such as intermittent and continuous TBS), the mechanisms for improving aphasia, and different stimulation plans for treating aphasia. It also discusses the limitations of current domestic and international research on TBS treatment for aphasia, aiming to provide new clinical references and insights for the rehabilitation treatment of post-stroke aphasia.

Key words: Stroke, Theta burst stimulation, Rehabilitation, Aphasia

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