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中华脑科疾病与康复杂志(电子版)

中华脑科疾病与康复杂志(电子版) ›› 2024, Vol. 14 ›› Issue (03) : 171 -176. doi: 10.3877/cma.j.issn.2095-123X.2024.03.008

综述

Theta爆发式经颅磁刺激治疗卒中后失语的研究进展
沈康敏1, 康晓宇2, 刘丽旭1,†()   
  1. 1. 325000　温州，温州医科大学第二临床医学院
    2. 100068　北京，中国康复研究中心神经康复一科
  • 收稿日期:2023-12-11 出版日期:2024-06-15
  • 通信作者: 刘丽旭

Research progress on the use of Theta burst stimulation for the treatment of post-stroke aphasia

Kangmin Shen1, Xiaoyu Kang2, Lixu Liu1,†()   

  1. 1. The Second Clinical Medical College of Wenzhou Medical University, Wenzhou 325000, China
    2. China Rehabilitation Research Centre, Beijing 100068, China
  • Received:2023-12-11 Published:2024-06-15
  • Corresponding author: Lixu Liu
  • Supported by:
    National Key Research and Development Program(2022YFC3602802)
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沈康敏, 康晓宇, 刘丽旭. Theta爆发式经颅磁刺激治疗卒中后失语的研究进展[J]. 中华脑科疾病与康复杂志(电子版), 2024, 14(03): 171-176.

Kangmin Shen, Xiaoyu Kang, Lixu Liu. Research progress on the use of Theta burst stimulation for the treatment of post-stroke aphasia[J]. Chinese Journal of Brain Diseases and Rehabilitation(Electronic Edition), 2024, 14(03): 171-176.

随着卒中发病率的不断上升，患病人群逐渐呈现年轻化趋势。卒中后语言功能障碍不仅会影响患者和他人的交流，而且会导致患者理解力下降、发音困难、情绪低落等，从而无法理解康复指令，难以配合康复训练，影响预后。Theta爆发式经颅磁刺激（TBS）作为一种新兴的经颅磁刺激模式，有助于卒中后失语患者语言能力的恢复，但其治疗方案却各不相同。本文围绕TBS的作用原理、不同刺激模式（如间歇性TBS和持续性TBS）的基本特征、改善失语的机制、治疗失语的不同刺激方案及目前国内外关于TBS治疗失语的相关研究所存在的局限性等方面展开综述，以期为卒中后失语的康复治疗提供新的临床参考和思路。

关键词: 卒中, Theta爆发式经颅磁刺激, 康复, 失语

Currently, the incidence of stroke is steadily increasing, and the patient population is gradually becoming younger. The resulting language impairments not only affect communication between patients and others, but also hinder the patient's understanding of recovery instructions due to decreased comprehension, speech difficulties, and emotional depression, making it challenging to cooperate with rehabilitation training. This, in turn, affects the overall prognosis of the patient. Theta burst stimulation (TBS), as an emerging transcranial magnetic stimulation modality, aids in the recovery of language abilities in post-stroke aphasia patients, but the treatment protocols vary widely. This article provides a comprehensive review of the principles of TBS, the basic characteristics of different stimulation modes (such as intermittent and continuous TBS), the mechanisms for improving aphasia, and different stimulation plans for treating aphasia. It also discusses the limitations of current domestic and international research on TBS treatment for aphasia, aiming to provide new clinical references and insights for the rehabilitation treatment of post-stroke aphasia.

Key words: Stroke, Theta burst stimulation, Rehabilitation, Aphasia
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