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中华脑科疾病与康复杂志(电子版) ›› 2017, Vol. 07 ›› Issue (02) : 103 -106. doi: 10.3877/cma.j.issn.2095-123X.2017.02.013

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综述

丘脑底核-脑深部电刺激对帕金森病非运动症状的影响
伊新艳1, 乔迪2, 张旋3,()   
  1. 1. 250022 济南,山东济南大学山东省医学科学院医学与生命科学学院;272000 山东济宁,山东省医学科学院附属济宁市第一人民医院神经内科
    3. 272000 山东济宁,山东省医学科学院附属济宁市第一人民医院神经内科
  • 收稿日期:2016-10-10 出版日期:2017-04-01
  • 通信作者: 张旋

Subthalamic nuclei-deep brain stimulation on motor symptoms in Parkinson′s disease

Xinyan Yi1, Di Qiao2, Xuan Zhang3,()   

  1. 1. School of Medicine and Life Sciences, University of Jinan-Shandong Academy of Medical Sciences, Jinan 250022 China
    2. School of Medicine and Life Sciences, University of Jinan-Shandong Academy of Medical Sciences, Jinan 250022 China; Department of Neurology, Affiliated Jining NO.1 People′s Hospital of Shandong Academy of Medical Sciences, Jining 272000, China
    3. Department of Neurology, Affiliated Jining NO.1 People′s Hospital of Shandong Academy of Medical Sciences, Jining 272000, China
  • Received:2016-10-10 Published:2017-04-01
  • Corresponding author: Xuan Zhang
  • About author:
    Corresponding author: Zhang Xuan, Email:
引用本文:

伊新艳, 乔迪, 张旋. 丘脑底核-脑深部电刺激对帕金森病非运动症状的影响[J/OL]. 中华脑科疾病与康复杂志(电子版), 2017, 07(02): 103-106.

Xinyan Yi, Di Qiao, Xuan Zhang. Subthalamic nuclei-deep brain stimulation on motor symptoms in Parkinson′s disease[J/OL]. Chinese Journal of Brain Diseases and Rehabilitation(Electronic Edition), 2017, 07(02): 103-106.

帕金森病(PD)是临床上仅次于阿尔茨海默病的第二常见的中老年神经系统退行性疾病,目前除了典型的运动症状外,还存在许多非运动症状(NMS),主要表现为睡眠障碍、吞咽困难、流涎、抑郁、认知、情感淡漠、自主神经功能障碍等,非运动症状机制复杂、发病时间不一、种类繁多。给患者及家属带来了沉重的生活负担。双侧丘脑底核-脑深部电刺激治疗帕金森病运动症状已经得到国内外的共识,但是对非运动症状改善效果仍是我们探讨的重点。

Parkinson′s disease (PD) is second only to Alzheimer′s disease clinical the second most common in middle-aged nervous system degenerative disease, in addition to the typical symptoms of motion at present, there are many non motor symptoms (NMS), main show is a sleep disorder, difficulty swallowing, salivate, depression, cognitive, emotional indifference, autonomic nerve dysfunction, etc. The movement mechanism of complex of symptoms, onset time is differ, phyletic and various.Bring to the patient and family burden of life.Bilateral subthalamic nuclei-deep brain electrical stimulation treatment on motor symptoms of Parkinson′s disease has been the consensus of both at home and abroad, but for the motor symptoms improvement effect is still the focus of our inquiry.

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